The results of various studies from 2010 have underlined the importance of the careful diagnostic assessment of GERD. Recent studies have also provided further evidence of the complex pathogenesis of GERD, and promising agents targeting the underlying factors in the pathogenesis of this condition are in the pipeline, especially for treatment-refractory GERD.
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Kandulski, A., Malfertheiner, P. Diagnosis, novel mechanisms of disease and promising agents. Nat Rev Gastroenterol Hepatol 8, 73–74 (2011). https://doi.org/10.1038/nrgastro.2010.220
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DOI: https://doi.org/10.1038/nrgastro.2010.220