Modelling

An abundance of data and unprecedented computational power are allowing sophisticated biological models to be devised and tested. This series of articles examines how the coupling of genetics with disciplines such as engineering, statistics, physics and computational biology has enriched our understanding in areas that range from developmental patterning to genetic association analyses.


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2009

December 2009 Volume 10 No 12

Synthetic biology: understanding biological design from synthetic circuits

Shankar Mukherji & Alexander van Oudenaarden

doi:10.1038/nrg2697

October 2009 Volume 10 No 10

Bayesian statistical methods for genetic association studies

Matthew Stephens & David J. Balding

doi:10.1038/nrg2615

September 2009 Volume 10 No 9

Microfluidic devices for measuring gene network dynamics in single cells

Matthew R. Bennett & Jeff Hasty

doi:10.1038/nrg2625

August 2009 Volume 10 No 8

Quantitative approaches in developmental biology

Andrew C. Oates, Nicole Gorfinkiel, Marcos González–Gaitán & Carl–Philipp Heisenberg

doi:10.1038/nrg2548

August 2009 Volume 10 No 8

Evolutionary analysis of the dynamics of viral infectious disease

Oliver G. Pybus & Andrew Rambaut

doi:10.1038/nrg2583

July 2009 Volume 10 No 7

From DNA sequence to transcriptional behaviour: a quantitative approach

Eran Segal & Jonathan Widom

doi:10.1038/nrg2591

June 2009 Volume 10 No 6

Detecting gene–gene interactions that underlie human diseases

Heather J. Cordell

doi:10.1038/nrg2579

February 2009 Volume 10 No 2

Stochastic modelling for quantitative description of heterogeneous biological systems

Darren J. Wilkinson

doi:10.1038/nrg2509

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