Current Issue

Featured article

Molecular and cellular mechanisms of CLL: novel therapeutic approaches

Lisa Pleyer, Alexander Egle, Tanja Nicole Hartmann & Richard Greil

The mainstay of therapy of chronic lymphocytic leukemia (CLL) is cytotoxic chemotherapy; however, CLL is still an incurable disease with resistance to therapy developing in a majority of patients. This Review summarizes the progress made in understanding the biological basis of CLL pathogenesis and other aspects of CLL biology, and describes novel treatment strategies that have also been exploited in current clinical trials.

Current Issue

Featured article

A stepwise approach to the management of metastatic midgut carcinoid tumor

Sanjeev Bhattacharyya, Dorothy M. Gujral, Christos Toumpanakis, Gilles Dreyfus, Brian R. Davidson, Joseph Davar & Martyn E. Caplin

The authors present a case of a 48-year-old man with a history of diarrhea, flushing and upper abdominal pain who was subsequently diagnosed with metastatic carcinoid tumor. The authors discuss the importance of a stepwise approach in a multi-disciplinary team setting to provide effective patient care.

Current Issue

Also in this issue

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  Review: Anticancer strategies involving the vasculature

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  Review: Surgical management of pancreatic endocrine tumors

• News and Views: Apples and oranges: the low and mid versus the upper rectum

Society News

ESO

The European School of Oncology (ESO) in partnership with Nature Reviews Clinical Oncology is pleased to announce the 56th e-grandround, entitled "The role of single agent rituximab in the treatment algorithm of follicular lymphoma". This topic will be discussed by Dr. Michele Ghielmini during a live webcast on Thursday 9 July 17:15–18:00 UK time. Online participants will be able to submit questions.

Please visit www.e-eso.net for further information.