Nature Reviews Clinical Oncology
Volume 6, No 12 December 2009
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Current Issue
Featured article
Liver metastases from colorectal cancer: radioembolization with systemic therapy
Nils H. Nicolay, David P. Berry & Ricky A. Sharma
Most patients with advanced colorectal cancer die from hepatic metastases. Radioembolization is a technique for administering radiotherapy internally to unresectable primary or secondary hepatic malignancies in a single procedure to improve local control of disease. This technique enables significant downsizing of liver metastases after surgical resection, and the rationale for this approach combined with cytotoxic and molecularly targeted agents is outlined.
Current Issue
Featured article
Targeted therapies: Sunitinib in RCC: expanded access equals expanded benefit?
Toni K. Choueiri & Michael B. Atkins
Sunitinib is a standard first-line therapy for patients with advanced or metastatic clear-cell renal cell carcinoma. In an expanded-access study, sunitinib has demonstrated clinical benefit with an acceptable safety profile in a population of patients that is representative of those seen in clinical practice.
Current Issue
Also in this issue
News and Views: Primary HPV screening for cervical cancer prevention: results from European trials
Elsebeth Lynge & Matejka Rebolj
Review: Histological and molecular types of breast cancer: is there a unifying taxonomy?
Britta Weigelt & Jorge S. Reis-Filho
Perpectives: More is less—combining targeted therapies in metastatic colorectal cancer
Cornelis J. A. Punt & Jolien Tol
Society News
ESO
The European School of Oncology (ESO) in partnership with Nature Reviews Clinical Oncology is pleased to announce the 77th e-grandround, entitled "Breast cancer and pregnancy: How safe is trastuzumab?" This presentation is based on a Review published in Nature Reviews Clinical Oncology. This topic will be discussed by the author Dr. Hatem Azim, during a live webcast on Thursday 3 December 17:15–18:00 UK time. Online participants will be able to submit questions.
Please visit www.e-eso.net for further information.
2008 Journal Citation Reports (Thomson Reuters, 2009). Nature Reviews Clinical Oncology was previously published as Nature Clinical Practice Oncology.


