Current Issue

Featured article

Liver metastases from colorectal cancer: radioembolization with systemic therapy

Nils H. Nicolay, David P. Berry & Ricky A. Sharma

Most patients with advanced colorectal cancer die from hepatic metastases. Radioembolization is a technique for administering radiotherapy internally to unresectable primary or secondary hepatic malignancies in a single procedure to improve local control of disease. This technique enables significant downsizing of liver metastases after surgical resection, and the rationale for this approach combined with cytotoxic and molecularly targeted agents is outlined.

Current Issue

Featured article

Targeted therapies: Sunitinib in RCC: expanded access equals expanded benefit?

Toni K. Choueiri & Michael B. Atkins

Sunitinib is a standard first-line therapy for patients with advanced or metastatic clear-cell renal cell carcinoma. In an expanded-access study, sunitinib has demonstrated clinical benefit with an acceptable safety profile in a population of patients that is representative of those seen in clinical practice.

Current Issue

Also in this issue

News and Views: Primary HPV screening for cervical cancer prevention: results from European trials

Elsebeth Lynge & Matejka Rebolj

Review: Histological and molecular types of breast cancer: is there a unifying taxonomy?

Britta Weigelt & Jorge S. Reis-Filho

Perpectives: More is less—combining targeted therapies in metastatic colorectal cancer

Cornelis J. A. Punt & Jolien Tol

Society News

ESO

The European School of Oncology (ESO) in partnership with Nature Reviews Clinical Oncology is pleased to announce the 77th e-grandround, entitled "Breast cancer and pregnancy: How safe is trastuzumab?" This presentation is based on a Review published in Nature Reviews Clinical Oncology. This topic will be discussed by the author Dr. Hatem Azim, during a live webcast on Thursday 3 December 17:15–18:00 UK time. Online participants will be able to submit questions.

Please visit www.e-eso.net for further information.