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Chromosome transfer between mature primate oocytes. Chromosomes from metaphase 2arrested oocytes are isolated into membrane- surrounded karyoplasts and placed into the perivetelline space of recipient-enucleated oocytes. Chromosomes are then introduced into these enucleated oocytes via membrane fusion. Image is from the protocol by Tachibana et al. (doi:10.1038/nprot.2010.75).