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Unless specifically designed to avoid it, nanoparticles adsorb biomolecules from their surroundings when they enter the biological environment. This corona of biomolecules forms the identity of the nanoparticles because it is this surface that interacts with biological systems. The importance of this corona has been seen in biomaterial implants and cell scaffolds. However, unlike macroscopic surfaces, nanoparticles can travel to almost every part of the organism and further exchange biomolecules along its path. In the Review by Kenneth Dawson and co-workers, they discuss the basic concepts of this corona and how its properties may be linked to the biological behaviour of nanoparticles. Key issues are outlined for future research. The concept is illustrated on the cover that shows a corona on a nanoparticle surface interacting with a receptor protruding from the cell lipid bilayer.
Treatment of mammalian cells with dilute silicic acid followed by heating forms silica replicas of the cell template, offering a way to preserve cell specimens and generate biocomposites for various applications.
Nanoparticles in contact with the biological environment adsorb a layer of biomolecules, which forms the biological identity of the particles. This Review outlines the concepts of the nanoparticle corona and how it interacts with biological systems, and assesses the critical problems to be resolved.
Magnetic circular dichroism reveals an enhancement of paramagnetism in copper-doped ZnSe–CdSe nanoscrystals and that the enhancement persists for hours in the dark.
A solution-processed ultraviolet photodetector with a nanocomposite active layer composed of ZnO nanoparticles blended with semiconducting polymers can significantly outperform inorganic photodetectors.
Mechanical metamaterials that have liquid-like properties when taken out of water and solid-like properties when in water can be prepared from DNA hydrogels.
A new signal generation mechanism based on the growth of gold nanoparticles offers a way to detect ultralow concentrations of analytes with the naked eye.
A supramolecular polymer with embedded nanostructured Ni particles shows mechanical and electrical self-healing capabilities as well as piezoresistive properties, making it a good candidate for electronic skin applications.