A cardiac-specific reporter genetically engineered into human embryonic stem cells allows the optimization of differentiation protocols and the identification of cell-surface markers—a welcome new tool to help isolate and define cardiac cell lineages.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Challenges in identifying the best source of stem cells for cardiac regeneration therapy
Stem Cell Research & Therapy Open Access 13 March 2015
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Elliott, D.A. et al. Nat. Methods 8, 1037–1040 (2011).
Dubois, N.C. et al. Nat. Biotechnol. published online, 10.1038/nbt.2005 (23 October 2011).
Wu, S.M. et al. Cell 127, 1137–1150 (2006).
Christoforou, N. et al. J. Clin. Invest. 118, 894–903 (2008).
Masino, A.M. et al. Circ. Res. 95, 389–397 (2004).
Bu, L. et al. Nature 460, 113–117 (2009).
Kita-Matsuo, H. et al. PLoS ONE 4, e5046 (2009).
He, J.Q., Ma, Y., Lee, Y., Thomson, J.A. & Kamp, T.J. Circ. Res. 93, 32–39 (2003).
Carvajal-Vergara, X. et al. Nature 465, 808–812 (2010).
Moretti, A. et al. N. Engl. J. Med. 363, 1397–1409 (2010).
Ieda, M. et al. Cell 142, 375–386 (2010).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
T.J.K. is a co-founder and consultant for Cellular Dynamics International, a company that uses human pluripotent stem cells and their derivatives for research, drug discovery and drug testing.
Rights and permissions
About this article
Cite this article
Kamp, T. Recognizing heart cells in a crowd. Nat Methods 8, 1013–1016 (2011). https://doi.org/10.1038/nmeth.1780
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmeth.1780
This article is cited by
-
Therapeutic potential of menstrual blood-derived endometrial stem cells in cardiac diseases
Cellular and Molecular Life Sciences (2019)
-
Challenges in identifying the best source of stem cells for cardiac regeneration therapy
Stem Cell Research & Therapy (2015)