Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Zinc-finger nucleases transition to the CoDA

Nature Methods volume 8, pages 53–55 (2011)Cite this article

Subjects

Potent and easily produced custom zinc-finger nucleases will be game-changers for the field, at a time when the field itself is changing.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Engineering improvements to ZFNs.

References

  1. Sander, J.D. et al. Nat. Methods 8, 67–69 (2011).

    Article  CAS  Google Scholar 

  2. Kim, S., Lee, M.J., Kim, H., Kang, M. & Kim, J.-S. Nat. Methods 8, 7–9 (2011).

    Article  CAS  Google Scholar 

  3. Doyon, Y. et al. Nat. Methods 8, 74–79 (2011).

    Article  CAS  Google Scholar 

  4. Maeder, M.L. et al. Mol. Cell 31, 294–301 (2008).

    Article  CAS  Google Scholar 

  5. Urnov, F.D., Rebar, E.J., Holmes, M.C., Zhang, H.S. & Gregory, P.D., Nat. Rev. Genet. 11, 636–646 (2010).

    Article  CAS  Google Scholar 

  6. Kim, H.J., Lee, H.J., Kim, H., Cho, S.W. & Kim, J.S., Genome Res. 19, 1279–1288 (2009).

    Article  CAS  Google Scholar 

  7. Miller, J.C. et al. Nat. Biotechnol. 25, 778–785 (2007).

    Article  CAS  Google Scholar 

  8. Szczepek, M. et al. Nat. Biotechnol. 25, 786–793 (2007).

    Article  CAS  Google Scholar 

  9. Christian, M. et al. Genetics 186, 757–761 (2010).

    Article  CAS  Google Scholar 

  10. Li, T. et al. Nucleic Acids Res. advance online publication 10 August 2010 (doi: 10.1093/nar/gkq704).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. David J. Segal is at the Genome Center and Department of Biochemistry and Molecular Medicine, University of California–Davis, Davis, California, USA.,

    David J Segal

Authors
  1. David J Segal
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to David J Segal.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Segal, D. Zinc-finger nucleases transition to the CoDA. Nat Methods 8, 53–55 (2011). https://doi.org/10.1038/nmeth0111-53

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nmeth0111-53

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research