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Redesigning CLIP for efficiency, accuracy and speed

Two new approaches for target profiling of RNA-binding proteins require less cell material, avoid radioactive reagents and give more accurate data in a shorter time compared to previous methods.

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Figure 1: Outline of the major steps of irCLIP and eCLIP.

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Correspondence to Mihaela Zavolan.

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Martin, G., Zavolan, M. Redesigning CLIP for efficiency, accuracy and speed. Nat Methods 13, 482–483 (2016). https://doi.org/10.1038/nmeth.3870

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