An algorithm called CONTACT identifies correlated side-chain motions in proteins from X-ray crystallographic data, providing insights into dynamics and function.
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References
van den Bedem, H. et al. Nat. Methods 10, 896–902 (2013).
Fraser, J.S. et al. Proc. Natl. Acad. Sci. USA 108, 16247–16252 (2011).
Lang, P.T. et al. Protein Sci. 19, 1420–1431 (2010).
Fraser, J.S. et al. Nature 462, 669–673 (2009).
Schnell, J.R., Dyson, H.J. & Wright, P.E. Annu. Rev. Biophys. Biomol. Struct. 33, 119–140 (2004).
Adamczyk, A.J. et al. Proc. Natl. Acad. Sci. USA 108, 14115–14120 (2011).
Bhabha, G. et al. Science 332, 234–238 (2011).
Caspar, D.L. et al. Nature 332, 659–662 (1988).
Wall, M.E., Ealick, S.E. & Gruner, S.M. Proc. Natl. Acad. Sci. USA 94, 6180–6184 (1997).
Wall, M.E. Methods Mol. Biol. 544, 269–279 (2009).
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Wilson, M. Visualizing networks of mobility in proteins. Nat Methods 10, 835–837 (2013). https://doi.org/10.1038/nmeth.2606
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DOI: https://doi.org/10.1038/nmeth.2606