Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
A single biomolecule carries information that becomes lost in an ensemble average. Methodological developments in imaging are now making it easier to access this hidden information in a live-cell context.