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An approach to form protein-based hydrogels in living cells that resemble physiological hydrogel-like size-dependent molecular sieves is presented. Synthetic RNA granules mimics are obtained by functionalizing these entities with RNA-binding motifs.
Integrins play an important role in the adhesion of cells to their matrix. Here, the authors investigate how fibroblasts respond to mechanical loads, at the onset of cell adhesion to fibronectin, in distinct phases that are modulated by integrins.
The physical properties of biomaterials affect cell behaviour. Here, the authors investigate how stiffness and degradation of hydrogels affect signalling pathways that modulate the maintenance of stemness of neural progenitor cells.
A structurally chiral two-dimensional array of nanomagnets is shown to thermally relax its magnetization by rotation in a preferential direction, behaving as a magnetic ratchet.
Organic resistive memories based on a spin-coated layer of a ruthenium complex with azo-aromatic ligands show high endurance, stability and fast switching speed, as well as good device reproducibility.
A microfluidics method to generate giant, copolymer-stabilized liposomes is presented. These vesicles are functionalized with distinct proteins to recapitulate cellular processes.
Stimulated emission under continuous-wave excitation from mercury telluride quantum dots at very low thresholds (compatible with electrical injection) is achieved by exploiting surface traps that render the quantum dots into four-level systems.
The structure and porosity of a zinc imidazolate framework above the melting point was studied with neutron and X-ray scattering, and molecular dynamics. The porosity and local bonding of the framework persist even in the liquid phase.
Circulating tumour DNA is used as a biomarker for cancer diagnosis. Here, the authors identified a DNA methylation biomarker for hepatocellular carcinoma and developed diagnostic and prognostic models to predict specificity and survival of patients.
Polarization-dependent photoluminescent mapping reveals that excitons — composite particles made of electron–hole pairs bound by the Coulomb force — exhibit the Hall effect, which originates from the large exciton Berry curvature.
Tissue mimics are of great interest in understanding diseases. Here, organoids were developed that resemble polycystic kidney disease cysts and it was demonstrated how material environment and adhesion can affect cystogenesis and disease progression.
The mechanical properties of biomaterials affect cell growth through mechanotransduction signals. Here, hydrogels with fast stress relaxation were developed and showed increased cartilage matrix formation by cartilage cells compared to slow relaxation hydrogels.
Fast field-driven antiferromagnetic spin dynamics is realized in ferrimagnetic Gd23Fe67.4Co9.6 thin films at the angular momentum compensation point. In particular, at this point, the field-driven domain wall mobility is found to be enhanced.
Lattices of exciton-polariton condensates provide the base for a simulator that can be used to find the global minimum of the classical XY Hamiltonian.
Self-replication and exponential growth are essential in nature. Here, the authors design a system of DNA origami rafts that exponentially replicate and demonstrate sensitivity to environmental changes.
Imaging of ferroelectric domain walls and their polarity is achieved through scanning stress microscopy. Twin boundaries are found to allow nanoscale gating of the two-dimensional electron gas at the LaAlO3/SrTiO3 interface.
Time-resolved ultrafast spectroscopy is combined with stimulated emission depletion microscopy to observe exciton migration in conjugated polymer films with nanometre and picosecond resolution.