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Crystal nucleation

Nucleus in a droplet

Real-time transmission electron microscopy shows that the formation of crystal nuclei of organic molecules in solution occurs inside dense liquid nanoclusters.

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Figure 1: Schematic of the two-step mechanism of nucleation of crystals of tribromide-Y on single-molecule hooks9.

References

  1. Erdemir, D., Lee, A. Y. & Myerson, A. S. Acc. Chem. Res. 42, 621–629 (2009).

    Article  CAS  Google Scholar 

  2. Vekilov, P. G. Cryst. Growth Design 10, 5007–5019 (2010).

    Article  CAS  Google Scholar 

  3. Galkin, O. & Vekilov, P. G. Proc. Natl Acad. Sci. USA 97, 6277–6281 (2000).

    Article  CAS  Google Scholar 

  4. Garetz, B., Matic, J. & Myerson, A. Phys. Rev. Lett. 89, 175501 (2002).

    Article  Google Scholar 

  5. Vekilov, P. G. Cryst. Growth Design 4, 671–685 (2004).

    Article  CAS  Google Scholar 

  6. Galkin, O. et al. Biophys. J. 93, 902–913 (2007).

    Article  CAS  Google Scholar 

  7. Savage, J. R. & Dinsmore, A. D. Phys. Rev. Lett. 102, 198302 (2009).

    Article  CAS  Google Scholar 

  8. Pouget, E. M. et al. Science 323, 1455–1458 (2009).

    Article  CAS  Google Scholar 

  9. Harano, K. et al. Nature Mater. 11, 877–881 (2012).

    Article  CAS  Google Scholar 

  10. Kashchiev, D. Nucleation: Basic Theory with Applications (Butterworth-Heinemann, 2000).

    Google Scholar 

  11. Milchev, A., Stoyanov, S. & Kaischev, R. Thin Solid Films 22, 255–265 (1974).

    Article  CAS  Google Scholar 

  12. Yau, S-T. & Vekilov, P. G. Nature 406, 494–497 (2000).

    Article  CAS  Google Scholar 

  13. Galkin, O. & Vekilov, P. G. J. Am. Chem. Soc. 122, 156–163 (2000).

    Article  CAS  Google Scholar 

  14. Filobelo, L. F., Galkin, O. & Vekilov, P. G. J. Chem. Phys. 123, 014904 (2005).

    Article  Google Scholar 

  15. Pan, W., Kolomeisky, A. B. & Vekilov, P. G. J. Chem. Phys. 122, 174905 (2005).

    Article  Google Scholar 

Download references

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Correspondence to Peter G. Vekilov.

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Vekilov, P. Nucleus in a droplet. Nature Mater 11, 838–840 (2012). https://doi.org/10.1038/nmat3441

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