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| Editorial |  Top |
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Mind your heart p305
doi:10.1038/nm0402-305
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| Letters to Editor | Top |
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Does neutrophil CD38 have a role in Ca++ signaling triggered by  2 integrin? p307
Sharon Dewitt, Iraj Laffafian
& Maurice B. Hallett
doi:10.1038/nm0402-307a
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Reply to 'Does neutrophil CD38 have a role in Ca++ signaling triggered by 2 integrin?' pp307 - 308
Frances E. Lund, Troy D. Randall
& Santiago Partida-Sánchez
doi:10.1038/nm0402-307b
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(58K)
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Dyslipidemia due to retroviral protease inhibitors p308
Anthony D. Kelleher, Andrew K. Sewell
& David A. Price
doi:10.1038/nm0402-308a
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Reply to 'Dyslipidemia due to retroviral protease inhibitors' pp308 - 309
Stephen L. Sturley, Oliver Distler, Jun-Shan Liang, David A. Cooper, Richard J. Deckelbaum
& Henry N. Ginsberg
doi:10.1038/nm0402-308b
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(58K)
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| News | Top |
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Will Zerhouni become the new NIH director? p311
Marlene Cimons
doi:10.1038/nm0402-311a
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(221K)
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Poor sales trigger vaccine withdrawal pp311 - 312
Emma Hitt
doi:10.1038/nm0402-311b
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(748K)
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Tech transfer pays off p312
Ken Garber
doi:10.1038/nm0402-312
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(575K)
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Ebola: small, but real progres p313
Karen Birmingham
& Sarah Cooney
doi:10.1038/nm0402-313
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(128K)
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Charity's first move is drug investment p314
Peter Mitchell
doi:10.1038/nm0402-314a
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(665K)
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Stem cell scientist moves to Singapore p314
Karen Birmingham
doi:10.1038/nm0402-314b
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New regulations give UK the lead in stem cell work p315
David Dickson
doi:10.1038/nm0402-315a
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Systems biology—the new R&D buzzword? pp315 - 316
Laura Bonetta
doi:10.1038/nm0402-315b
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(714K)
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Nature Medicine/UCSD/Salk conference rewards physician-scientists p316
Karen Birmingham
doi:10.1038/nm0402-316
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Barry Bloom p317
Karen Birmingham
doi:10.1038/nm0402-317
Abstract | Full text | PDF
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| Commentary | Top |
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CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause? pp319 - 323
Zvi Grossman, Martin Meier-Schellersheim, Ana E. Sousa, Rui M.M. Victorino
& William E. Paul
doi:10.1038/nm0402-319
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(95K)
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| Book Reviews | Top |
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Who Owns Academic Work? Battling for Control of Intellectual Property p325
Reviewed by: Sheldon Krimsky
doi:10.1038/nm0402-325
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(237K)
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Stem Cells and the Future of Regenerative Medicine p326
Reviewed by: Connie Eaves
doi:10.1038/nm0402-326
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(428K)
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| News and Views | Top |
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New anti-HSV therapeutics target the helicase−primase complex pp327 - 328
Clyde S. Crumpacker
& Priscilla A. Schaffer
doi:10.1038/nm0402-327
Abstract | Full text | PDF
(80K)
See also: Article by Crute et al. | Article by Kleymann et al. |
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Polygenic or Pollyanna? pp328 - 330
William D. Foulkes
doi:10.1038/nm0402-328
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Weak mitochondria permit protein clumps in Down syndrome p330
Charlotte Schubert
doi:10.1038/nm0402-330
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Juvenile autoimmune diabetes: A pathogenic role for maternal antibodies? pp331 - 333
Matthias von Herrath
& Jean-Francois Bach
doi:10.1038/nm0402-331
Abstract | Full text | PDF
(82K)
See also: Article by Greeley et al. |
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Antibody gene therapy: Old wine in a new bottle pp333 - 334
Lieping Chen
doi:10.1038/nm0402-333
Abstract | Full text | PDF
(92K)
See also: Article by Ye et al. |
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Block the FAS, lose the fat pp335 - 336
Charles V. Mobbs
& Hideo Makimura
doi:10.1038/nm0402-335
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(170K)
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The skinny on CD39 in immunity and inflammation pp336 - 338
Richard D. Granstein
doi:10.1038/nm0402-336
Abstract | Full text | PDF
(94K)
See also: Article by Mizumoto et al. |
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Not just research tools—proteasome inhibitors offer therapeutic promise pp338 - 340
Alfred L. Goldberg
& Kenneth Rock
doi:10.1038/nm0402-338
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Research News p341
Charlotte Schubert, Charlotte Wang
& Paul Morin
doi:10.1038/nm0402-341
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(459K)
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| Articles | Top |
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Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB pp343 - 348
Zhengmao Ye, Ingegerd Hellström, Martha Hayden-Ledbetter, Amber Dahlin, Jeffrey A. Ledbetter
& Karl Erik Hellström
doi:10.1038/nm0402-343
Abstract | Full text | PDF
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See also: News and Views by Chen |
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Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium−derived factor pp349 - 357
Olga V. Volpert, Tetiana Zaichuk, Wei Zhou, Frank Reiher, Thomas A. Ferguson, P. Michael Stuart, Mohammad Amin
& Noel P. Bouck
doi:10.1038/nm0402-349
Abstract | Full text | PDF
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CD39 is the dominant Langerhans cell−associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness pp358 - 365
Norikatsu Mizumoto, Tadashi Kumamoto, Simon C. Robson, Jean Sévigny, Hiroyuki Matsue, Keiichi Enjyoji
& Akira Takashima
doi:10.1038/nm0402-358
Abstract | Full text | PDF
(415K)
See also: News and Views by Granstein |
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Efomycine M, a new specific inhibitor of selectin, impairs leukocyte adhesion and alleviates cutaneous inflammation pp366 - 372
Michael P. Schön, Thomas Krahn, Margarete Schön, Maria-L. Rodriguez, Horst Antonicek, Jeanette E. Schultz, Ralf J. Ludwig, Thomas M. Zollner, Erwin Bischoff, Klaus-D. Bremm, Matthias Schramm, Kerstin Henninger, Roland Kaufmann, Harald P. M. Gollnick, Christina M. Parker
& W.-Henning Boehncke
doi:10.1038/nm0402-366
Abstract | Full text | PDF
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Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection pp373 - 378
Manfred Kopf, Brian Abel, Awen Gallimore, Michael Carroll
& Martin F. Bachmann
doi:10.1038/nm0402-373
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(243K)
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Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections pp379 - 385
Victor Appay, P. Rod Dunbar, Margaret Callan, Paul Klenerman, Geraldine M.A. Gillespie, Laura Papagno, Graham S. Ogg, Abigail King, Franziska Lechner, Celsa A. Spina, Susan Little, Diane V. Havlir, Douglas D. Richman, Norbert Gruener, Gerd Pape, Anele Waters, Philippa Easterbrook, Mariolina Salio, Vincenzo Cerundolo, Andrew J. McMichael
& Sarah L. Rowland-Jones
doi:10.1038/nm0402-379
Abstract | Full text | PDF
(2,335K)
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Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease pp386 - 391
James J. Crute, Christine A. Grygon, Karl D. Hargrave, Bruno Simoneau, Anne-Marie Faucher, Gordon Bolger, Philip Kibler, Michel Liuzzi
& Michael G. Cordingley
doi:10.1038/nm0402-386
Abstract | Full text | PDF
(125K)
See also: News and Views by Crumpacker & Schaffer |
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New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease pp392 - 398
Gerald Kleymann, Rüdiger Fischer, Ulrich A.K. Betz, Martin Hendrix, Wolfgang Bender, Udo Schneider, Gabriele Handke, Peter Eckenberg, Guy Hewlett, Veniamin Pevzner, Judith Baumeister, Olaf Weber, Kerstin Henninger, Jörg Keldenich, Axel Jensen, Jörg Kolb, Ute Bach, Andreas Popp, Jutta Mäben, Isabelle Frappa, Dieter Haebich, Oswald Lockhoff
& Helga Rübsamen-Waigmann
doi:10.1038/nm0402-392
Abstract | Full text | PDF
(1,165K)
See also: News and Views by Crumpacker & Schaffer |
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Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice pp399 - 402
Siri Atma W. Greeley, Makoto Katsumata, Liping Yu, George S. Eisenbarth, Daniel J. Moore, Heidi Goodarzi, Clyde F. Barker, Ali Naji
& Hooman Noorchashm
doi:10.1038/nm0402-399
Abstract | Full text | PDF
(201K)
See also: News and Views by von Herrath & Bach |
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Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis pp403 - 409
Masataka Sata, Akio Saiura, Atsushi Kunisato, Akihiro Tojo, Seiji Okada, Takeshi Tokuhisa, Hisamaru Hirai, Masatoshi Makuuchi, Yasunobu Hirata
& Ryozo Nagai
doi:10.1038/nm0402-403
Abstract | Full text | PDF
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In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens pp410 - 414
Anne M. Dickinson, Xiao-Nong Wang, Lisbet Sviland, Florry A. Vyth-Dreese, Graham H. Jackson, Ton N.M. Schumacher, John B.A.G. Haanen, Tuna Mutis
& Els Goulmy
doi:10.1038/nm0402-410
Abstract | Full text | PDF
(2,743K)
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| New Technology | Top |
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Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery pp415 - 419
John A. Mikszta, Jason B. Alarcon, John M. Brittingham, Diane E. Sutter, Ronald J. Pettis
& Noel G. Harvey
doi:10.1038/nm0402-415
Abstract | Full text | PDF
(1,010K)
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On the market p419
doi:10.1038/nm0402-419
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(489K)
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