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Antibody gene therapy: Old wine in a new bottle

Nature Medicine volume 8, pages 333–334 (2002)Cite this article

Tumor cells engineered to overexpress molecules that activate an immune response have shown therapeutic promise in preventing growth of cancers. In a new study, tumor cells studded with a ligand-mimicking antibody fragment beckon their own destruction. (pages 343–348)

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Figure 1: Potential mechanisms for 4-1BB antibody gene therapy.

Kimberly Homer

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Authors and Affiliations

  1. Department of Immunology Mayo Graduate and Medical Schools Mayo Clinic, Rochester, Minnesota

    Lieping Chen

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  1. Lieping Chen
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Chen, L. Antibody gene therapy: Old wine in a new bottle. Nat Med 8, 333–334 (2002). https://doi.org/10.1038/nm0402-333

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