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| Editorial |  Top |
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Heading off a web of deceit p1
doi:10.1038/83226
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| Letters to Editor | Top |
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TNF- is not the cause of fatty liver disease in obese diabetic mice pp2 - 3
Riaz A. Memon, Carl Grunfeld
& Kenneth R. Feingold
doi:10.1038/83316
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(24K)
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Reply to 'TNF- is not the cause of fatty liver disease in obese diabetic mice' pp2 - 3
Anna Mae Diehl
doi:10.1038/83319
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(82K)
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| News | Top |
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Tobacco issues resurface in Europe p5
Karen Birmingham
doi:10.1038/83343
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(1,536K)
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UK names leading cancer centers p6
David Dickson
doi:10.1038/83374
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(143K)
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Wilson faces life ban p6
Karen Birmingham
doi:10.1038/83376
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(143K)
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US clamp down on web pharmacies p6
Laura Bonetta
doi:10.1038/83378
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(143K)
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FDA uneasy about placebo revision p7
Tom Hollon
doi:10.1038/83389
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(22K)
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West coast US recognizes academic gender bias p7
Tinker Ready
doi:10.1038/83391
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(22K)
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Stiff penalty for vision researcher guilty of scientific misconduct p8
Tinker Ready
doi:10.1038/83409
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(139K)
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Final policy on federal misconduct issued p8
Karen Birmingham
doi:10.1038/83411
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(139K)
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Tonga joins list of laboratory communities p8
Rada Rouse
doi:10.1038/83413
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(139K)
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Is investment in bioterrorism research warranted p9
Alan Dove
doi:10.1038/83424
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(97K)
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US publishes records of HIV/AIDS efforts p9
Myrna E. Watanabe
doi:10.1038/83426
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(97K)
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Harold Varmus p10
Karen Birmingham
doi:10.1038/83228
Abstract | Full text | PDF
(321K)
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| Commentaries | Top |
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A post-genomic perspective pp11 - 13
Douglas B. Young
doi:10.1038/83250
Abstract | Full text | PDF
(63K)
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Fighting tobacco dependence in Europe pp13 - 14
Martin Raw
doi:10.1038/83281
Abstract | Full text | PDF
(30K)
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| Book Reviews | Top |
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Betrayal of Trust: The Collapse of Global Public Health p15
Reviewed by: Ron Gray
doi:10.1038/83283
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(231K)
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The Eradication of Smallpox: Edward Jenner and The First and Only Eradication of a Human Infectious Disease pp15 - 16
Reviewed by: Kevin M. De Cock
doi:10.1038/83286
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(569K)
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| News and Views | Top |
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Is tissue plasminogen activator a threat to neurons? pp17 - 18
Stephen F. Traynelis
& Stuart A. Lipton
doi:10.1038/83289
Abstract | Full text | PDF
(264K)
See also: Article by Nicole et al. |
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Amyloid  vaccination: reduced plaques and improved cognition pp18 - 19
Steven G. Younkin
doi:10.1038/83929
Abstract | Full text | PDF
(237K)
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A new entry route for HIV pp20 - 21
Bryan R. Cullen
doi:10.1038/83295
Abstract | Full text | PDF
(52K)
See also: Article by Saha et al. |
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Yersinia lead SUMO attack pp21 - 23
Guy R. Cornelis
& Geertrui Denecker
doi:10.1038/83298
Abstract | Full text | PDF
(539K)
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Progress in cardiovascular biology: PPAR for the course pp23 - 24
Mitchell A. Lazar
doi:10.1038/83301
Abstract | Full text | PDF
(49K)
See also: Article by Moore et al. | Article by Chawla et al. | Article by Chinetti et al. |
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Hitting the reset button for immune tolerance pp24 - 25
Allan D. Kirk
doi:10.1038/83304
Abstract | Full text | PDF
(46K)
See also: Article by Anderson & Matzinger |
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A SADS defect in tumor cells provides optimism pp26 - 27
Hiroshi Takahashi
doi:10.1038/83306
Abstract | Full text | PDF
(53K)
See also: Article by Suzuki et al. |
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NO vascular control in Duchenne muscular dystrophy pp27 - 29
Rachelle H. Crosbie
doi:10.1038/83309
Abstract | Full text | PDF
(732K)
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Forbidden fruit pp29 - 30
J. K. Aronson
doi:10.1038/83312
Abstract | Full text | PDF
(616K)
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| Research News |
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Research News p31
Kristine Novak, Karen Birmingham
& Bernd Pulverer
doi:10.1038/83321
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(178K)
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| Review | Top |
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Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics pp33 - 40
Mark A. Kay, Joseph C Glorioso
& Luigi Naldini
doi:10.1038/83324
Abstract | Full text | PDF
(111K)
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| Articles | Top |
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The role of PPAR- in macrophage differentiation and cholesterol uptake pp41 - 47
Kathryn J. Moore, Evan D. Rosen, Michael L. Fitzgerald, Felix Randow, Lorna P. Andersson, David Altshuler, David S. Milstone, Richard M. Mortensen, Bruce M. Spiegelman
& Mason W. Freeman
doi:10.1038/83328
Abstract | Full text | PDF
(836K)
See also: News and Views by Lazar |
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PPAR- dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation pp48 - 52
Ajay Chawla, Yaacov Barak, Laszlo Nagy, Debbie Liao, Peter Tontonoz
& Ronald M. Evans
doi:10.1038/83336
Abstract | Full text | PDF
(600K)
See also: News and Views by Lazar |
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PPAR- and PPAR- activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway pp53 - 58
Giulia Chinetti, Sophie Lestavel, Virginie Bocher, Alan T. Remaley, Bernadette Neve, Inés Pineda Torra, Elisabeth Teissier, Anne Minnich, Michael Jaye, Nicolas Duverger, H. Bryan Brewer, Jean-Charles Fruchart, Véronique Clavey
& Bart Staels
doi:10.1038/83348
Abstract | Full text | PDF
(1,377K)
See also: News and Views by Lazar |
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The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling pp59 - 64
Olivier Nicole, Fabian Docagne, Carine Ali, Isabelle Margaill, Peter Carmeliet, Eric T. MacKenzie, Denis Vivien
& Alain Buisson
doi:10.1038/83358
Abstract | Full text | PDF
(1,001K)
See also: News and Views by Traynelis & Lipton |
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Isolation of primary HIV-1 that target CD8+ T Lymphocytes using CD8 as a receptor pp65 - 72
Kunal Saha, Jianchao Zhang, Anil Gupta, Rajnish Dave, Meron Yimen
& Bouchra Zerhouni
doi:10.1038/83365
Abstract | Full text | PDF
(2,038K)
See also: News and Views by Cullen |
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Increased production of IL-7 accompanies HIV-1−mediated T-cell depletion: implications for T-cell homeostasis pp73 - 79
Laura A. Napolitano, Robert M. Grant, Steven G. Deeks, Diane Schmidt, Stephen C. De Rosa, Leonore A. Herzenberg, Brian G. Herndier, Jan Andersson
& Joseph M. McCune
doi:10.1038/83381
Abstract | Full text | PDF
(1,014K)
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Immunity or tolerance: Opposite outcomes of microchimerism from skin grafts pp80 - 87
Colin C. Anderson
& Polly Matzinger
doi:10.1038/83393
Abstract | Full text | PDF
(1,443K)
See also: News and Views by Kirk |
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SADS: A new component of Fas-DISC is the accelerator for cell death signaling and is downregulated in patients with colon carcinoma pp88 - 93
Atsushi Suzuki, Shigehiro Obata, Midori Hayashida, Hirokazu Kawano, Takeshi Nakano
& Katsuya Shiraki
doi:10.1038/83401
Abstract | Full text | PDF
(3,374K)
See also: News and Views by Takahashi |
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Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells pp94 - 100
Kazuyoshi Takeda, Yoshihiro Hayakawa, Mark J. Smyth, Nobuhiko Kayagaki, Noriko Yamaguchi, Shigeru Kakuta, Yoichiro Iwakura, Hideo Yagita
& Ko Okumura
doi:10.1038/83416
Abstract | Full text | PDF
(1,089K)
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Impaired prostate tumorigenesis in Egr1-deficient mice pp101 - 107
Sarki A. Abdulkadir, Zhican Qu, Emily Garabedian, Sheng-Kwei Song, Thomas J. Peters, John Svaren, Joseph M. Carbone, Cathy K. Naughton, William J. Catalona, Joseph J.H. Ackerman, Jeffrey I. Gordon, Peter A. Humphrey
& Jeffrey Milbrandt
doi:10.1038/83231
Abstract | Full text | PDF
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Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation pp108 - 113
Francisco Garcia Soriano, László Virág, Prakash Jagtap, Éva Szabó, Jon G. Mabley, Lucas Liaudet, Anita Marton, Dale G. Hoyt, Kanneganti G. K. Murthy, Andrew L. Salzman, Garry J. Southan
& Csaba Szabó
doi:10.1038/83241
Abstract | Full text | PDF
(1,206K)
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IL-15 and IL-2: a matter of life and death for T cells in vivo pp114 - 118
Xian Chang Li, Gulcin Demirci, Sylvie Ferrari-Lacraz, Chris Groves, Anthony Coyle, Thomas R. Malek
& Terry B. Strom
doi:10.1038/83253
Abstract | Full text | PDF
(141K)
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Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway pp119 - 122
Kanchan Chitaley, Christopher J. Wingard, R. Clinton Webb, Heather Branam, Vivienne S. Stopper, Ronald W. Lewis
& Thomas M. Mills
doi:10.1038/83258
Abstract | Full text | PDF
(62K)
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| New Technology | Top |
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Direct isolation and sequencing of specific protein-binding glycosaminoglycans pp123 - 128
Nishla Keiser, Ganesh Venkataraman, Zachary Shriver
& Ram Sasisekharan
doi:10.1038/83263
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(498K)
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On the market p128
doi:10.1038/83270
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(427K)
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| Errata | Top |
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ERRATA p129
doi:10.1038/83276
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(104K)
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CORRECTION p129
doi:10.1038/83297
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(104K)
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