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| Editorial |  Top |
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US guidelines on xenotransplantation p465
doi:10.1038/8325
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(32K)
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| Letters to Editor | Top |
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Osteogenesis imperfecta calls for caution-first letter p466
Joan C. Marini
doi:10.1038/8326
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(29K)
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Osteogenesis imperfecta calls for caution-second letter p466
N.J. Bishop
doi:10.1038/8528
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(40K)
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Reply to osteogenesis imperfecta calls for caution pp466 - 467
Edwin M. Horwitz, Darwin J. Prockop, Lorraine A. Fitzpatrick, Winston W.K. Koo, Jeffrey C. Marx
& Malcolm K. Brenner
doi:10.1038/8327
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(34K)
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Adeno-associated virus 2 co-receptors? p467
Jianming Qiu, Hiro Mizukami
& Kevin E. Brown
doi:10.1038/8328
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(64K)
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Adeno-associated virus 2 co-receptors?-first reply p468
Keyun Qing, Jonathan Hansen
& Arun Srivastava
doi:10.1038/8526
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(55K)
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Adeno-associated virus 2 co-receptors?-second reply p468
Richard Jude Samulski, Jeffrey S. Bartlett
& Candance Summerford
doi:10.1038/8330
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(55K)
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| News | Top |
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Report calculates value for money of US vaccine R&D p469
Karen Birmingham
doi:10.1038/8332
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(69K)
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The sun sets on the CVI pp469 - 470
Karen Birmingham
doi:10.1038/8334
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(106K)
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NIAID to begin clinical transplant tolerance trials pp470 - 471
Kristine Novak
doi:10.1038/8336
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(100K)
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Genome sequencers square off down under p471
Rada Rouse
doi:10.1038/8338
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(48K)
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US lead in immunology research threatened p471
Karen Birmingham
doi:10.1038/8339
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(48K)
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Is research suffering at academic health centers? p472
Alicia Ault
doi:10.1038/8340
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(35K)
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Italy promises to increase focus on rare diseases pp472 - 473
Martina Ballmaier
doi:10.1038/8343
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(72K)
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Mixed success in NHS-research collaboration p473
David Dickson
doi:10.1038/8345
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(59K)
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Japan moves towards experimental tissue regulation p473
Robert Triendl
doi:10.1038/8346
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(59K)
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Smallpox stocks: new focus for research? p474
Alan Dove
doi:10.1038/8347
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(117K)
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Researcher charged with data theft p474
Stephen Cass
doi:10.1038/8350
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(117K)
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| Obituary | Top |
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Russell Ross
1929−1999 p475
Peter Libby
doi:10.1038/8351
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(77K)
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| Commentary | Top |
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Clinical research is dead; long live clinical research pp477 - 478
John I. Bell
doi:10.1038/8353
Abstract | Full text | PDF
(34K)
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| Book Reviews | Top |
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Scientific American Molecular Neurology p479
Reviewed by: Solomon H. Snyder
doi:10.1038/8354
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(89K)
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Viruses and Human Cancer pp479 - 480
Reviewed by: Harald zur Hausen
doi:10.1038/8356
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(156K)
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The Molecules Within Us pp480 - 481
Reviewed by: Jennifer Fosmire
doi:10.1038/8358
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(146K)
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Transcription Factors and Human Disease pp481 - 482
Reviewed by: Rossella Tupler
& Michael R. Green
doi:10.1038/8360
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(129K)
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| News and Views | Top |
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Dangerous T-cell amnesia pp483 - 484
Guy Gorochov
doi:10.1038/8362
Abstract | Full text | PDF
(185K)
See also: Article by Pitcher et al. |
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The Holy Grail of influenza virologists pp484 - 485
John S. Oxford
& Rod S. Daniels
doi:10.1038/8364
Abstract | Full text | PDF
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Shrinking prions: new folds to old questions pp486 - 487
Adriano Aguzzi
& Sebastian Brandner
doi:10.1038/8366
Abstract | Full text | PDF
(230K)
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Evolution of the fittest ends in tragedy pp488 - 489
Vanessa M. Hirsch
doi:10.1038/8369
Abstract | Full text | PDF
(962K)
See also: Article by Kimata et al. |
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Thalidomide on the comeback trail pp489 - 490
Barbara F. Hales
doi:10.1038/8371
Abstract | Full text | PDF
(108K)
See also: Article by Parman et al. |
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P53 escape from P19ARF-trapped MDM2 p490
Sara Mariani
doi:10.1038/8372
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(98K)
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Therapeutic angiogenesis for heart failure pp491 - 492
Jeffrey M. Isner
& Douglas W. Losordo
doi:10.1038/8374
Abstract | Full text | PDF
(105K)
See also: Article by Carmeliet et al. |
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Towards the global elimination of trachoma pp492 - 493
Hugh Taylor
doi:10.1038/8376
Abstract | Full text | PDF
(114K)
See also: Article by Lietman et al. |
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| Articles | Top |
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Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice
lacking the vascular endothelial growth factor isoforms VEGF164
and VEGF188 pp495 - 502
Peter Carmeliet, Yin-Shan Ng, Dieter Nuyens, Gregor Theilmeier, Koen Brusselmans, Ivo Cornelissen, Elisabeth Ehler, Vijay V. Kakkar, Ingeborg Stalmans, Virginie Mattot, Jean-Claude Perriard, Mieke Dewerchin, Willem Flameng, Andras Nagy, Florea Lupu, Lieve Moons, Désiré Collen, Patricia A. D'Amore
& David T. Shima
doi:10.1038/8379
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(670K)
See also: News and Views by Isner & Losordo |
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Calpain 3 deficiency is associated with myonuclear apoptosis and profound
perturbation of the I B /NF-B pathway in limb-girdle muscular
dystrophy type 2A pp503 - 511
Stephen Baghdiguian, Marianne Martin, Isabelle Richard, Françoise Pons, Catherine Astier, Nathalie Bourg, Ronald T. Hay, Raymond Chemaly, Georges Halaby, Jacques Loiselet, Louise V. B. Anderson, Adolfo Lopez de Munain, Michel Fardeau, Paul Mangeat, Jacques S. Beckmann
& Gérard Lefranc
doi:10.1038/8385
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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy pp512 - 517
Diana Finzi, Joel Blankson, Janet D. Siliciano, Joseph B. Margolick, Karen Chadwick, Theodore Pierson, Kendall Smith, Julianna Lisziewicz, Franco Lori, Charles Flexner, Thomas C. Quinn, Richard E. Chaisson, Eric Rosenberg, Bruce Walker, Stephen Gange, Joel Gallant
& Robert F. Siliciano
doi:10.1038/8394
Abstract | Full text | PDF
(446K)
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HIV-1-specific CD4+ T cells are detectable in most individuals
with active HIV-1 infection, but decline with prolonged viral suppression
pp518 - 525
Christine J. Pitcher, Claudia Quittner, Dolores M. Peterson, Mark Connors, Richard A. Koup, Vernon C. Maino
& Louis J. Picker
doi:10.1038/8400
Abstract | Full text | PDF
(728K)
See also: News and Views by Gorochov |
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Neutralizing antibody-independent containment of immunodeficiency virus
challenges by DNA priming and recombinant pox virus booster immunizations
pp526 - 534
Harriet L. Robinson, David C. Montefiori, R. Paul Johnson, Kelledy H. Manson, Marcia L. Kalish, Jeffrey D. Lifson, Tahir A. Rizvi, Shan Lu, Shiu-Lok Hu, Gail P. Mazzara, Dennis L. Panicali, James G. Herndon, Rhona Glickman, Maria A. Candido, Shari L. Lydy, Michael S. Wyand
& Harold M. McClure
doi:10.1038/8406
Abstract | Full text | PDF
(132K)
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Emerging cytopathic and antigenic simian immunodeficiency virus variants
influence AIDS progression pp535 - 541
Jason T. Kimata, LaRene Kuller, David B. Anderson, Peter Dailey
& Julie Overbaugh
doi:10.1038/8414
Abstract | Full text | PDF
(132K)
See also: News and Views by Hirsch |
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Regulation of Fas ligand expression and cell death by apoptosis-linked
gene 4 pp542 - 547
Emanuela Lacana'
& Luciano D'Adamio
doi:10.1038/8420
Abstract | Full text | PDF
(303K)
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CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma
and bypasses T-cell help pp548 - 553
Ruth R. French, H.T. Claude Chan, Alison L. Tutt
& Martin J. Glennie
doi:10.1038/8426
Abstract | Full text | PDF
(122K)
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NF-B is activated and promotes cell death in focal cerebral ischemia
pp554 - 559
Armin Schneider, Ana Martin-Villalba, Falk Weih, Johannes Vogel, Thomas Wirth
& Markus Schwaninger
doi:10.1038/8432
Abstract | Full text | PDF
(534K)
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Transgenic mice with Alzheimer presenilin 1 mutations show accelerated
neurodegeneration without amyloid plaque formation pp560 - 564
De-Hua Chui, Hiroshi Tanahashi, Kazuharu Ozawa, Sachiya Ikeda, Frédéric Checler, Otoya Ueda, Hiroshi Suzuki, Wataru Araki, Haruhisa Inoue, Keiro Shirotani, Keikichi Takahashi, Ferenc Gallyas
& Takeshi Tabira
doi:10.1038/8438
Abstract | Full text | PDF
(994K)
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Altered peptide ligands narrow the repertoire of cellular immune responses
by interfering with T-cell priming pp565 - 571
Magdalena Plebanski, Edwin A.M. Lee, Carolyn M. Hannan, Katie L. Flanagan, Sarah C. Gilbert, Michael B. Gravenor
& Adrian V.S. Hill
doi:10.1038/8444
Abstract | Full text | PDF
(139K)
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Global elimination of trachoma: How frequently should we administer mass
chemotherapy? pp572 - 576
Tom Lietman, Travis Porco, Chandler Dawson
& Sally Blower
doi:10.1038/8451
Abstract | Full text | PDF
(80K)
See also: News and Views by Taylor |
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Enhanced inhibition of hepatitis B virus production by asialoglycoprotein
receptor-directed interferon pp577 - 581
Toshiharu Eto
& Hiroshi Takahashi
doi:10.1038/8462
Abstract | Full text | PDF
(88K)
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Free radical-mediated oxidative DNA damage in the mechanism of thalidomide
teratogenicity pp582 - 585
Toufan Parman, Michael J. Wiley
& Peter G. Wells
doi:10.1038/8466
Abstract | Full text | PDF
(83K)
See also: News and Views by Hales |
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| New Technology | Top |
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Viral receptors and vector purification: New approaches for generating clinical-grade reagents pp587 - 588
Candace Summerford
& Richard Jude Samulski
doi:10.1038/8470
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(250K)
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On the market p589
doi:10.1038/8473
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(125K)
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| Errata | Top |
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Selective changes in single cell GABAA receptor expression and function
in temporal lobe epilepsy p590
A.R. Brooks-Kayal, M.D. Shumate, H. Jin, T.Y. Rikhter
& D.A. Coulter
doi:10.1038/8477
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(26K)
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Fusion of monocytes and macrophages with HIV-1 correlates with biochemical
properties of CXCR4 and CCR5 p590
C.K. Lapham, M.B. Zaitseva, S. Lee, T. Romanstseva
& H. Golding
doi:10.1038/8858
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(26K)
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Live attenuated, multiply deleted simian immunodeficiency virus causes
AIDS in infant and adult macaques p590
T.W. Baba, V. Liska, A.H. Khimani, N.B. Ray, P.J. Dailey, D. Penninck, R. Bronson, M.F. Greene, H.M. McClure, L.N. Martin
& R.M. Ruprecht
doi:10.1038/8859
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(26K)
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