News and Views
Nature Immunology 9, 1095 - 1096 (2008)
doi:10.1038/ni1008-1095
Putting ThPOK in place
J Jeremiah Bell1 & Avinash Bhandoola1
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J. Jeremiah Bell and Avinash Bhandoola are in the Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
e-mail: bhandooa@mail.med.upenn.edu
Abstract
ThPOK is necessary for the differentiation of CD4+ helper T cells. Three new studies indicate that, unexpectedly, ThPOK is required only after initial specification to the CD4+ lineage.
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