Table of contents


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Editorial

Stepping up to the plate p1

doi:10.1038/ni0108-1


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Commentary

Mentoring and networking: how to make it work pp3 - 5

Laura Haynes, Sherrill L Adams & Jeremy M Boss

doi:10.1038/ni0108-3


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News and Views

Akirins versus infection pp7 - 9

Bruce Beutler & Eva Marie Y Moresco

doi:10.1038/ni0108-7

See also: Article by Goto et al.


IRF1: a deus ex machina in TH1 differentiation pp9 - 10

Derya Unutmaz & Jan Vilcek

doi:10.1038/ni0108-9

See also: Article by Kano et al.


Antigens take the shuttle pp11 - 12

Georg Kraal

doi:10.1038/ni0108-11

See also: Article by Cinamon et al.


Bring out your dead pp12 - 14

David A Hume

doi:10.1038/ni0108-12


Research Highlights p15

doi:10.1038/ni0108-15


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Articles

Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain pp25 - 33

Thirumalai R Ramalingam, John T Pesce, Faruk Sheikh, Allen W Cheever, Margaret M Mentink-Kane, Mark S Wilson, Sean Stevens, David M Valenzuela, Andrew J Murphy, George D Yancopoulos, Joseph F Urban, Jr, Raymond P Donnelly & Thomas A Wynn

doi:10.1038/ni1544



The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics pp42 - 53

Levi G Ledgerwood, Girdhari Lal, Nan Zhang, Alexandre Garin, Steven J Esses, Florent Ginhoux, Miriam Merad, Helene Peche, Sergio A Lira, Yaozhong Ding, Yu Yang, Xingxuan He, Edward H Schuchman, Maria L Allende, Jordi C Ochando & Jonathan S Bromberg

doi:10.1038/ni1534


Follicular shuttling of marginal zone B cells facilitates antigen transport pp54 - 62

Guy Cinamon, Marcus A Zachariah, Olivia M Lam, Frank W Foss, Jr & Jason G Cyster

doi:10.1038/ni1542

See also: News and Views by Kraal


CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand pp63 - 72

David Depoil, Sebastian Fleire, Bebhinn L Treanor, Michele Weber, Naomi E Harwood, Kevin L Marchbank, Victor L J Tybulewicz & Facundo D Batista

doi:10.1038/ni1547




Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release–activated calcium channels pp89 - 96

Monika Vig, Wayne I DeHaven, Gary S Bird, James M Billingsley, Huiyun Wang, Patricia E Rao, Amy B Hutchings, Marie-Hélène Jouvin, James W Putney & Jean-Pierre Kinet

doi:10.1038/ni1550

See also: Article by Baba et al.


Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice pp97 - 104

Akira Goto, Kazufumi Matsushita, Viola Gesellchen, Laure El Chamy, David Kuttenkeuler, Osamu Takeuchi, Jules A Hoffmann, Shizuo Akira, Michael Boutros & Jean-Marc Reichhart

doi:10.1038/ni1543

See also: News and Views by Beutler & Moresco


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Erratum

Erratum: Pathogen subversion of cell-intrinsic innate immunity p105

Craig R Roy & Edward S Mocarski

doi:10.1038/ni0108-105a


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Corrigenda

Corrigendum: The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways p105

Rossana Zaru, Natalia Ronkina, Matthias Gaestel, J Simon C Arthur & Colin Watts

doi:10.1038/ni0108-105b


Corrigendum: Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-bold gamma p105

Jamie R Schoenborn, Michael O Dorschner, Masayuki Sekimata, Deanna M Santer, Maria Shnyreva, David R Fitzpatrick, John A Stamatoyannopoulos & Christopher B Wilson

doi:10.1038/ni0108-105c


Corrigendum: Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27–stimulated T cells p105

Denise C Fitzgerald, Guang-Xian Zhang, Mohamed El-Behi, Zoë Fonseca-Kelly, Hongmei Li, Shuo Yu, Christiaan J Saris, Bruno Gran, Bogoljub Ciric & Abdolmohamad Rostami

doi:10.1038/ni0108-105d


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