A signaling module consisting of the adaptor ADAP and the Carma1–Bcl-10–MALT1 (CBM)–TAK1 signalosome has been shown to selectively induce cytokine secretion but not cytotoxicity in natural killer cells.
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E.V. is cofounder and shareholder of Innate Pharma.
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Vivier, E., Ugolini, S. & Nunès, J. ADAPted secretion of cytokines in NK cells. Nat Immunol 14, 1108–1110 (2013). https://doi.org/10.1038/ni.2737
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DOI: https://doi.org/10.1038/ni.2737
