Limiting immune responses is critical for protecting the host from harm. The p110δ isoform of the kinase PI(3)K acts as a balance between pro- and anti-inflammatory TLR4 signaling in dendritic cells.
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Siegemund, S., Sauer, K. Balancing pro- and anti-inflammatory TLR4 signaling. Nat Immunol 13, 1031–1033 (2012). https://doi.org/10.1038/ni.2452
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DOI: https://doi.org/10.1038/ni.2452
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