Enhancers and transcription factor binding sites that control cell-specific transcription in higher eukaryotes can be found up to hundreds of kilobases from the promoters that they control, making their identification challenging. A new study uses a model based on histone modifications and chromatin dynamics to predict functional elements involved in androgen receptor response.
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Morse, R. Epigenetic marks identify functional elements. Nat Genet 42, 282–284 (2010). https://doi.org/10.1038/ng0410-282
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DOI: https://doi.org/10.1038/ng0410-282