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Epigenetic marks identify functional elements

Enhancers and transcription factor binding sites that control cell-specific transcription in higher eukaryotes can be found up to hundreds of kilobases from the promoters that they control, making their identification challenging. A new study uses a model based on histone modifications and chromatin dynamics to predict functional elements involved in androgen receptor response.

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Figure 1: Identifying functional regulatory elements.

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Correspondence to Randall H Morse.

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Morse, R. Epigenetic marks identify functional elements. Nat Genet 42, 282–284 (2010). https://doi.org/10.1038/ng0410-282

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