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Published online 6 December 2007 | Nature | doi:10.1038/news.2007.347
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Stem cells treat anaemia in mice
Results provide proof of principle for therapeutic promise of induced pluripotent stem cells.
Researchers have successfully treated sickle-cell anemia in mice by using stem-cell lines created from cells at the tip of a mouse tail. It is the first demonstration that ‘induced pluripotent stem cells’ — adult cells that have been reprogrammed to behave more like embryonic stem cells — can be used therapeutically.
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It may be that different diseases will be best treated by using different kinds of stem cells, or even combinations of stem cells 我支�这观点（I sustain this point of view）
This is not a big deal!!! Chinese (led by a physician named Rong-Xiang Xu) has done in vivo regeneration of many different tissues by in situ activation of regenerative stem cells with just some compounds. Their technique is fully described in patents filed in China, Japan and USA so choose a language that you know to read it. I have read the English version of the US patent (6991813 B2) which is very impressive. For more clinical information you can also visit the website http://mebo.com which has links to the Chinese version and the English version of the website. /// PS: I do not know the above person working on regenerative medicine in China and just heard of his story several days ago. Shi V. Liu SVL@logibio.com http://im1.biz
Bravo to Jaenisch and his colleagues. I wonder if he agrees with Snyder's point regarding embryonic stem cells: "One needs to compare them head-to-head, and let the data dictate which is the safest and which is the most efficacious." The data speaks and IP cells have shown more promise and they avoid the ethical pitfalls of ES cells; why not just pursue the former?