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Published online 7 December 2006 | Nature | doi:10.1038/news061204-13

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New test could weed out dangerous drug trials

High-risk drugs such as antibodies need better safety checks, say experts.

Immunologists studying what went wrong in the fateful Northwick Park drug trial in London in March 2006 have developed a test that they say may have spotted the near-deadly effects of the 'superantibody' drug TGN1412.

The announcement came at the unveiling of a report by the expert scientific group convened to provide guidelines to the Medicines and Healthcare Products Regulatory Agency (MHRA), which governs UK clinical trials.

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