Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 5 Issue 5, May 2002

Even when the events around us are random, it can be hard to resist the temptation to make predictions about upcoming events based on apparent patterns (for instance, betting on black in roulette because the previous five runs have come up black). Gregory McCarthy and colleagues now suggest that the prefrontal cortex is involved in making such moment-to-moment predictions. The authors used functional MRI to image brain activity while subjects viewed random sequences composed of two stimuli and found that prefrontal cortex was activated when a particular stimulus violated an apparent pattern. See pages 394 and 485.

Editorial

Top of page ⤴

News & Views

  • NMDA receptors are important for both normal transmission and pathological damage. New results indicate that receptor location makes the key difference: survival-promoting signals derive from synaptic receptors, whereas a cell-death signal comes from extrasynaptic receptors.

    • Antonella Riccio
    • David D. Ginty
    News & Views
  • Neurons in primary visual cortex have long been classified into simple and complex cells, but a new paper notes that different firing patterns need not imply different underlying circuitry.

    • L F Abbott
    • Frances S. Chance
    News & Views
  • Two reports demonstrate more convincingly than ever that progeny of adult hippocampal stem cells become functional neurons in vitro and integrate into existing circuitry in vivo.

    • Thomas A. Reh
    News & Views
  • The brain continually attempts to extract patterns from environmental events. A new report suggests that this process depends on prefrontal cortex.

    • Richard Ivry
    • Robert T. Knight
    News & Views
Top of page ⤴

Book Review

Top of page ⤴

Brief Communication

Top of page ⤴

Article

Top of page ⤴

Erratum

Top of page ⤴

Corrigendum

Top of page ⤴

Search

Quick links