Nat. Neurosci. 5, 239–246 (2002)
Due to a printing error, the green in Fig. 2a was difficult to see. The corrected figure is reprinted below.
(a) Illustration of the FRAP method. Fluorescent actin monomers (green barbs) and filaments are free or bound to mobile or immobile proteins (black rectangles and circles), and the binding affinities can be regulated. Selective photobleaching of actin in the spine is followed by rapid exchange of mobile monomers (free and bound) with the dendritic region and recovery of fluorescence. If actin filaments do not turn over, filamentous actin will remain nonfluorescent (top panels) and the spine will not recover its fluorescence. On the other hand, if filaments are turning over rapidly, fluorescent monomers will be continuously incorporated into them and the bleached actin monomers will be exchanged out of the spine. The spine will thus recover its fluorescence (bottom panels).
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The online version of the original article can be found at 10.1038/nn811
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Star, E., Kwiatkowski, D. & Murthy, V. Erratum: Rapid turnover of actin in dendritic spines and its regulation by activity. Nat Neurosci 5, 500 (2002). https://doi.org/10.1038/nn0502-500a
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DOI: https://doi.org/10.1038/nn0502-500a
