A new study connects dietary polyunsaturated fatty acid intake to endocannabinoid-mediated neuronal function. Animals with specific fatty acid depletion show deficits in endocannabinoid-mediated synaptic depression and altered emotional behaviors.
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References
Logan, A.C. Lipids Health Dis. 3, 25 (2004).
Stahl, L.A., Begg, D.P., Weisinger, R.S. & Sinclair, A.J. Curr. Opin. Investig. Drugs 9, 57–64 (2008).
Lafourcade, M. et al. Nat. Neurosci. 14, 345–350 (2011).
Simopoulos, A.P. Biomed. Pharmacother. 56, 365–379 (2002).
Marszalek, J.R. & Lodish, H.F. Annu. Rev. Cell Dev. Biol. 21, 633–657 (2005).
Innis, S.M. J. Nutr. 137, 855–859 (2007).
Banni, S. & Di Marzo, V. Mol. Nutr. Food Res. 54, 82–92 (2010).
Kano, M., Ohno-Shosaku, T., Hashimotodani, Y., Uchigashima, M. & Watanabe, M. Physiol. Rev. 89, 309–380 (2009).
Orr, S.K. & Bazinet, R.P. Curr. Opin. Investig. Drugs 9, 735–743 (2008).
Kauer, J.A. & Malenka, R.C. Nat. Rev. Neurosci. 8, 844–858 (2007).
Matias, I. & Di Marzo, V. Trends Endocrinol. Metab. 18, 27–37 (2007).
Christensen, R., Kristensen, P.K., Bartels, E.M., Bliddal, H. & Astrup, A. Lancet 370, 1706–1713 (2007).
Di Marzo, V. & Szallasi, A. Br. J. Pharmacol. 154, 915–917 (2008).
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DiLeone, R. Neuroscience gets nutrition. Nat Neurosci 14, 271–272 (2011). https://doi.org/10.1038/nn0311-271
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DOI: https://doi.org/10.1038/nn0311-271