Editor-in-Chief: Vincent T DeVita, Jr, MD
Nature Clinical Practice Oncology delivers timely interpretations of key research developments, translating the latest findings into clinical practice. Our Editor-in-Chief and international Advisory Board ensure comprehensive coverage of topical issues throughout the year, with the highest standards of editorial quality and integrity that are hallmarks of Nature Publishing Group.
Table of Contents: May 2008
Free featured article
Drug Insight: gastrointestinal and hepatic adverse effects of molecular-targeted agents in cancer therapy
Yohann Loriot, Gabriel Perlemuter, David Malka, Frédérique Penault-Lorca, Valérie Boige, Eric Deutsch, Christophe Massard, Jean Pierre Armand and Jean-Charles Soria
Several toxicities are associated with molecular-targeted drugs including gastrointestinal adverse effects. These adverse effects need to be considered carefully because they can lead to the discontinuation of oral treatment and subsequently compromise cancer control. The authors of this Review discuss the incidence and clinical patterns of the gastrointestinal toxic effects induced by these agents and propose some hypotheses for each adverse event.
Free featured article
Should adjuvant imatinib be used as primary treatment for gastrointestinal stromal tumors?
Peter Hohenberger
Gastrointestinal stromal tumors that metastasize cannot be controlled by systemic chemotherapy or radiotherapy; however, tumor control in such patients can be achieved with imatinib. The author of this Viewpoint discusses whether imatinib should be used as adjuvant therapy in patients who are at risk for developing metastasis, and whether tumor size is an appropriate criterion for such therapy.
ESO e-grandround
The European School of Oncology (ESO) in partnership with Nature Clinical Practice Oncology is pleased to announce the ninth e-grandround, entitled "Stereotactic radiotherapy for stage I NSCLC: the triumph of technology over biology?". This topic is based on a Viewpoint article published in Nature Clinical Practice Oncology by David Ball and H Rodney Withers, and will be discussed by Dr J Belderbos during a live webcast on Thursday 8 May 17:15–18:00 UK time. Online participants will be able to submit questions.
Please visit www.e-eso.net for further information.
American Society for Clinical Oncology
Attending ASCO Annual Meeting in Chicago this May?
Come and see us at Booth 8120 and pick up your complimentary copy of Nature Clinical Practice Oncology.
We hope to see you there!
Forthcoming articles
Don't miss the following articles that will soon be appearing in the pages of Nature Clinical Practice Oncology!
World Cancer Congress
BIT Life Sciences is proud to announce that the World Cancer Congress with the theme of "From Basic Research to Therapeutics", will be held during June 12–17 in Shanghai. This unique event will provide spectacular professional development, learning and networking opportunities for all professionals working in the cancer field.
For more information, visit www.bitlifesciences.com/cancer2008/.