Advance online publication
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publicationBrief Communications
Diverse backbone-cyclized peptides via codon reprogramming
Takashi Kawakami, Atsushi Ohta, Masaki Ohuchi, Hiroshi Ashigai, Hiroshi Murakami & Hiroaki Suga
Published online: 25 October 2009 | doi:10.1038/nchembio.259

Abstract - Diverse backbone-cyclized peptides via codon reprogramming | Full Text - Diverse backbone-cyclized peptides via codon reprogramming | PDF (503 KB) - Diverse backbone-cyclized peptides via codon reprogramming | Supplementary information | Chemical compounds
LC/MS analysis of cellular RNA reveals NAD-linked RNA
Y Grace Chen, Walter E Kowtoniuk, Isha Agarwal, Yinghua Shen & David R Liu
Published online: 11 October 2009 | doi:10.1038/nchembio.235

Abstract - LC/MS analysis of cellular RNA reveals NAD-linked RNA | Full Text - LC/MS analysis of cellular RNA reveals NAD-linked RNA | PDF (276 KB) - LC/MS analysis of cellular RNA reveals NAD-linked RNA | Supplementary information | Chemical compounds
Articles
A synergistic small-molecule combination directly eradicates diverse prion strain structures
Blake E Roberts, Martin L Duennwald, Huan Wang, Chan Chung, Nicholas P Lopreiato, Elizabeth A Sweeny, M Noelle Knight & James Shorter
Published online: 01 November 2009 | doi:10.1038/nchembio.246

Abstract - A synergistic small-molecule combination directly eradicates diverse prion strain structures | Full Text - A synergistic small-molecule combination directly eradicates diverse prion strain structures | PDF (2,104 KB) - A synergistic small-molecule combination directly eradicates diverse prion strain structures | Supplementary information | Chemical compounds
Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis
Amparo Ruiz, Asier González, Ivan Muñoz, Raquel Serrano, J Albert Abrie, Erick Strauss & Joaquín Ariño
Published online: 01 November 2009 | doi:10.1038/nchembio.243

Abstract - Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis | Full Text - Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis | PDF (1,292 KB) - Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis | Supplementary information | Chemical compounds
Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem
Hao Song, Stephen Payne, Meagan Gray & Lingchong You
Published online: 01 November 2009 | doi:10.1038/nchembio.244

Abstract - Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem | Full Text - Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem | PDF (624 KB) - Spatiotemporal modulation of biodiversity in a synthetic chemical-mediated ecosystem | Supplementary information | Chemical compounds
Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation
Lynette Cegelski, Jerome S Pinkner, Neal D Hammer, Corinne K Cusumano, Chia S Hung, Erik Chorell, Veronica Åberg, Jennifer N Walker, Patrick C Seed, Fredrik Almqvist, Matthew R Chapman & Scott J Hultgren
Published online: 25 October 2009 | doi:10.1038/nchembio.242

Abstract - Small-molecule inhibitors target : Escherichia coli: amyloid biogenesis and biofilm formation | Full Text - Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation | PDF (1,412 KB) - Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation | Supplementary information | Chemical compounds
Natural amino acids do not require their native tRNAs for efficient selection by the ribosome
Philip R Effraim, Jiangning Wang, Michael T Englander, Josh Avins, Thomas S Leyh, Ruben L Gonzalez Jr & Virginia W Cornish
Published online: 25 October 2009 | doi:10.1038/nchembio.255

Abstract - Natural amino acids do not require their native tRNAs for efficient selection by the ribosome | Full Text - Natural amino acids do not require their native tRNAs for efficient selection by the ribosome | PDF (556 KB) - Natural amino acids do not require their native tRNAs for efficient selection by the ribosome | Supplementary information | Chemical compounds
The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA
Robert C Kelly, Megan E Bolitho, Douglas A Higgins, Wenyun Lu, Wai-Leung Ng, Philip D Jeffrey, Joshua D Rabinowitz, Martin F Semmelhack, Frederick M Hughson & Bonnie L Bassler
Published online: 18 October 2009 | doi:10.1038/nchembio.237

Abstract - The : Vibrio cholerae: quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA | Full Text - The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA | PDF (625 KB) - The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA | Supplementary information | Chemical compounds
Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome
Maria Manosas, Michelle M Spiering, Zhihao Zhuang, Stephen J Benkovic & Vincent Croquette
Published online: 18 October 2009 | doi:10.1038/nchembio.236

Abstract - Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome | Full Text - Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome | PDF (3,286 KB) - Coupling DNA unwinding activity with primer synthesis in the bacteriophage T4 primosome | Supplementary information
Dynamic refolding of IFN-
mRNA enables it to function as PKR activator and translation template
Smadar Cohen-Chalamish, Anat Hasson, Dahlia Weinberg, Lise Sarah Namer, Yona Banai, Farhat Osman & Raymond Kaempfer
Published online: 04 October 2009 | doi:10.1038/nchembio.234

Abstract - Dynamic refolding of IFN-[gamma] mRNA enables it to function as PKR activator and translation template | Full Text - Dynamic refolding of IFN-
mRNA enables it to function as PKR activator and translation template | PDF (2,609 KB) - Dynamic refolding of IFN-
mRNA enables it to function as PKR activator and translation template |
Supplementary information
Until print versions of AOP papers are published, they should be cited in the style "Author(s) Nature Chemical Biology advance online publication, day month year (doi:10.1038/nchembioXXXXX)". Once the print version (identical to the AOP) is published, it should be cited as follows: "Author(s) Nature Chemical Biology volume, page (year); advance online publication, (doi:10.1038/nchembioXXXXX)".
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