Reprogramming intercellular mechanotransduction and signaling pathways is still challenging. A recent advance uses a plug-and-play DNA nanodevice to allow non-mechanosensitive receptor tyrosine kinase (RTK) to transmit force-induced cellular signals.
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Ali, A.A., Tabrizi, M.A. & You, M. Forced rewiring of RTK signaling. Nat Chem Biol (2024). https://doi.org/10.1038/s41589-024-01604-6
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DOI: https://doi.org/10.1038/s41589-024-01604-6
