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RNA structure

Riboswitch strikes a chord

Nature Chemical Biology volume 7, pages 660–661 (2011)Cite this article

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Purine riboswitches have served as models for riboswitch structure, dynamics, evolution and engineering. New crystallographic models reveal the adaptability of a purine riboswitch evolved to bind 2′-deoxyguanosine and highlight challenges inherent to riboswitch engineering.

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Figure 1: A depiction of a subset of ligands that have been co-crystallized in complex with either natural or engineered purine riboswitches.

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  1. Charles E. Dann III is in the Department of Chemistry, Indiana University, Bloomington, Indiana, USA.,

    Charles E Dann III

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  1. Charles E Dann III
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Correspondence to Charles E Dann III.

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The author declares no competing financial interests.

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Dann, C. Riboswitch strikes a chord. Nat Chem Biol 7, 660–661 (2011). https://doi.org/10.1038/nchembio.672

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