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Protein labelling

Playing tag with proteins

Nature Chemistry volume 4, pages 248–250 (2012)Cite this article

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Fluorescent labels can now be attached to a specific protein on the surface of live cells using a two-step method that reacts a norbornene — introduced using genetic encoding — with a variety of dyes.

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Figure 1: Strategies for fluorescent tagging of proteins.

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Authors and Affiliations

  1. Dante Romanini and Virginia Cornish are in the Department of Chemistry at Columbia University, Northwest Corner Building, 550 West 120th Street, MC 4854, New York, New York 10027, USA,

    Dante W. Romanini & Virginia W. Cornish

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  1. Dante W. Romanini
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  2. Virginia W. Cornish
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Correspondence to Dante W. Romanini or Virginia W. Cornish.

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Romanini, D., Cornish, V. Playing tag with proteins. Nature Chem 4, 248–250 (2012). https://doi.org/10.1038/nchem.1325

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