Appreciating data: warts, wrinkles and all - p203

doi:10.1038/ncb0306-203a

Full Text - Appreciating data: warts, wrinkles and all | PDF (112 KB) - Appreciating data: warts, wrinkles and all

Nature Protocols - p203

doi:10.1038/ncb0306-203b

Full Text - Nature Protocols | PDF (112 KB) - Nature Protocols

Sketching the cinematic scientist - p204

Jay P. Telotte reviews Mad, Bad and Dangerous? The Scientist and the Cinema by Christopher Frayling

doi:10.1038/ncb0306-204

Full Text - Sketching the cinematic scientist | PDF (123 KB) - Sketching the cinematic scientist

Exporting actin - pp205 - 207

Joseph G. Gall

doi:10.1038/ncb0306-205

Actin is the most abundant protein in the giant oocyte nucleus of the frog Xenopus. It reaches this high concentration because the oocyte lacks exportin-6, a nuclear export factor that specifically pumps actin out of other nuclei. What effect actin has on the physical properties of the oocyte nucleus is a matter of ongoing debate.

Full Text - Exporting actin | PDF (298 KB) - Exporting actin

See also: Article by Bohnsack et al.

Sealed with a X - pp207 - 209

Céline Morey & Wendy Bickmore

doi:10.1038/ncb0306-207

At the onset of mammalian X-chromosome inactivation, the X chromosomes are counted and then a choice is made about which one to inactivate. New findings provide evidence that a transient physical association between X chromosomes in the nucleus might be involved in this process.

Full Text - Sealed with a X | PDF (203 KB) - Sealed with a X

See also: Letter by Bacher et al.

How APC/C orders destruction - pp209 - 211

Bettina A. Buschhorn & Jan-Michael Peters

doi:10.1038/ncb0306-209

The anaphase-promoting complex/cyclosome (APC/C) is a ubiquitin ligase that controls cell-cycle progression by targeting proteins for destruction by the 26S proteasome. The APC/C is active throughout late mitosis and G1 phase but APC/C substrates are degraded in a specific order. A recent study provides insights into how ordered turnover of substrates is achieved.

Full Text - How APC/C orders destruction | PDF (198 KB) - How APC/C orders destruction

Repressed by a NuRD - pp212 - 214

Jeremy M. Crook, N. Ray Dunn & Alan Colman

doi:10.1038/ncb0306-212

Embryonic stem (ES) cells deficient in Mbd3, a component of the nucleosome remodelling complex (NuRD), exhibit LIF-independent self-renewal and a restricted potential to differentiate. As such, it is likely that NuRD is required for ES cell pluripotency, and represents a potential link between maintaining the undifferentiated state and the capacity to differentiate.

Full Text - Repressed by a NuRD | PDF (455 KB) - Repressed by a NuRD

See also: Letter by Kaji et al.

Myosin II functions in actin-bundle turnover in neuronal growth cones - pp216 - 226

Nelson A. Medeiros, Dylan T. Burnette & Paul Forscher

doi:10.1038/ncb1367

Abstract - | Full Text - Myosin II functions in actin-bundle turnover in neuronal growth cones | PDF (1,392 KB) - Myosin II functions in actin-bundle turnover in neuronal growth cones | Supplementary information

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis - pp227 - 237

Huaye Zhang & Ian G. Macara

doi:10.1038/ncb1368

Abstract - | Full Text - The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis | PDF (11,380 KB) - The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis | Supplementary information

GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution - pp238 - 248

Manojkumar A. Puthenveedu, Collin Bachert, Sapna Puri, Frederick Lanni & Adam D. Linstedt

doi:10.1038/ncb1366

Abstract - | Full Text - GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution | PDF (1,175 KB) - GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution | Supplementary information

Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism - pp249 - 256

Lindy Abas, René Benjamins, Nenad Malenica, Tomasz Paciorek, Justyna Winiewska, Jeanette C. Moulinier–Anzola, Tobias Sieberer, Jií Friml & Christian Luschnig

doi:10.1038/ncb1369

Abstract - | Full Text - Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism | PDF (2,000 KB) - Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism | Supplementary information

A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes - pp257 - 263

Markus T. Bohnsack, Theis Stüven, Christa Kuhn, Volker C. Cordes & Dirk Görlich

doi:10.1038/ncb1357

Abstract - | Full Text - A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes | PDF (653 KB) - A selective block of nuclear actin export stabilizes the giant nuclei of Xenopus oocytes | Supplementary information

See also: News and Views by Gall

A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules - pp264 - 270

Tara L. Culver–Hanlon, Stephanie A. Lex, Andrew D. Stephens, Nicholas J. Quintyne & Stephen J. King

doi:10.1038/ncb1370

First Paragraph - | Full Text - A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules | PDF (979 KB) - A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules | Supplementary information

Retinoic-acid signalling in node ectoderm and posterior neural plate directs left–right patterning of somitic mesoderm - pp271 - 277

Ioan Ovidiu Sirbu & Gregg Duester

doi:10.1038/ncb1374

First Paragraph - | Full Text - Retinoic-acid signalling in node ectoderm and posterior neural plate directs left–right patterning of somitic mesoderm | PDF (1,188 KB) - Retinoic-acid signalling in node ectoderm and posterior neural plate directs left–right patterning of somitic mesoderm

The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation - pp278 - 284

Irina Naguibneva, Maya Ameyar-Zazoua, Anna Polesskaya, Slimane Ait-Si-Ali, Reguina Groisman, Mouloud Souidi, Sylvain Cuvellier & Annick Harel-Bellan

doi:10.1038/ncb1373

First Paragraph - | Full Text - The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation | PDF (547 KB) - The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation | Supplementary information

The NuRD component Mbd3 is required for pluripotency of embryonic stem cells - pp285 - 292

Keisuke Kaji, Isabel Martín Caballero, Ruth MacLeod, Jennifer Nichols, Valerie A. Wilson & Brian Hendrich

doi:10.1038/ncb1372

First Paragraph - | Full Text - The NuRD component Mbd3 is required for pluripotency of embryonic stem cells | PDF (961 KB) - The NuRD component Mbd3 is required for pluripotency of embryonic stem cells | Supplementary information

See also: News and Views by Crook et al.

Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation - pp293 - 299

Christian P. Bacher, Michèle Guggiari, Benedikt Brors, Sandrine Augui, Philippe Clerc, Philip Avner, Roland Eils & Edith Heard

doi:10.1038/ncb1365

First Paragraph - | Full Text - Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation | PDF (795 KB) - Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation | Supplementary information

See also: News and Views by Morey & Bickmore

Corrigendum - p299

doi:10.1038/ncb1375

Full Text - Corrigendum | PDF (27 KB) - Corrigendum

Corrigendum - p299

doi:10.1038/ncb1376

Full Text - Corrigendum | PDF (22 KB) - Corrigendum

Retraction - p299

doi:10.1038/ncb1377

Full Text - Retraction | PDF (28 KB) - Retraction