An actin filament coat promotes cargo expulsion from large exocytosing vesicles, but the mechanisms of coat formation and force generation have been poorly characterized. Elegant imaging studies of the Drosophila melanogaster salivary gland now reveal how actin and myosin are recruited, and show that myosin II forms a contractile 'cage' that facilitates exocytosis.
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Change history
04 February 2016
In the version of this News and Views article originally published, the author's affiliation was incorrect. This was corrected online on 4 February 2016.
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Merrifield, C. Actin puts the squeeze on Drosophila glue secretion. Nat Cell Biol 18, 142–144 (2016). https://doi.org/10.1038/ncb3305
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DOI: https://doi.org/10.1038/ncb3305
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