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Efficient generation of adipocytes in a dish

A protocol for efficient differentiation of human pluripotent stem cells into white and brown adipocytes now enables their detailed examination at a cellular and molecular level, facilitating the study of adipocyte dysfunction in a range of metabolic diseases including diabetes, heart disease and obesity.

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Figure 1: Generation of white and brown adipocytes from human pluripotent stem cells.
Figure 2: Reprogramming strategies to derive patient-specific differentiated lineages.

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Correspondence to Andrew G. Elefanty.

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The authors declare no competing financial interests.

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Elefanty, A., Stanley, E. Efficient generation of adipocytes in a dish. Nat Cell Biol 14, 126–127 (2012). https://doi.org/10.1038/ncb2430

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