Proteome-wide identification of ubiquitination events reveals their functional classes and identifies substrates for ubiquitin ligases.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
Nature Communications Open Access 20 December 2017
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Kim, W. et al. Mol. Cell 44, 325–340 (2011).
Wagner, S.A. et al. Mol. Cell. Proteomics 10, M111.013284 (2011).
Emanuele, M.J. et al. Cell 147, 459–474 (2011).
Hershko, A. & Ciechanover, A. Annu. Rev. Biochem. 67, 425–479 (1998).
Deshaies, R.J. & Joazeiro, C.A. Annu. Rev. Biochem. 78, 399–434 (2009).
Wilkinson, K.D. et al. Biochemistry 34, 14535–14546 (1995).
Deng, L. et al. Cell 103, 351–361 (2000).
Xu, G., Paige, J.S. & Jaffrey, S.R. Nat. Biotechnol. 28, 868–873 (2010).
Schubert, U. et al. Nature 404, 770–774 (2000).
Yen, H.C., Xu, Q., Chou, D.M., Zhao, Z. & Elledge, S.J. Science 322, 918–923 (2008).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
Cornell University and the authors may be entitled to royalties on the sale of certain antibodies that can be used for ubiquitin proteomic research.
Rights and permissions
About this article
Cite this article
Xu, G., Jaffrey, S. The new landscape of protein ubiquitination. Nat Biotechnol 29, 1098–1100 (2011). https://doi.org/10.1038/nbt.2061
Published:
Issue Date:
DOI: https://doi.org/10.1038/nbt.2061
This article is cited by
-
Post-translational modifications in tumor-associated carbonic anhydrases
Amino Acids (2022)
-
Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer
Nature Communications (2017)
-
Ubiquitin carboxyl-terminal hydrolases: involvement in cancer progression and clinical implications
Cancer and Metastasis Reviews (2017)
-
Endoplasmic reticulium protein profiling of heat-stressed Jurkat cells by one dimensional electrophoresis and liquid chromatography tandem mass spectrometry
Cytotechnology (2016)
-
Could Dysregulation of UPS be a Common Underlying Mechanism for Cancer and Neurodegeneration? Lessons from UCHL1
Cell Biochemistry and Biophysics (2013)