Volume 22 Issue 6, June 2004

Sanofi takeover jeopardizes Aventis biotech deals

• Peter Mitchell

EGFR inhibitors square off at ASCO

• Monya Baker

China ramps up efforts to commercialize GM rice

• Hepeng Jia
• K.S. Jayaraman
• Sabine Louët

New EU antitrust law burdens licensing

• Sabine Louët

Startups hope federal study fixes SBIR flaws

• Paroma Basu

News In Brief

Oligo oligarchy—the surprisingly small world of aptamers

• Karl Thiel

Surge in US patents on botanicals

• RK Gupta

Chasing 'transgenic' shadows

• Henry I Miller
• Gregory Conko

Drugs in crops (continued)

• Gregory C Phillips

ELSI and bioterrorism countermeasures?

• Shane K Green

Preprocessing of oligonucleotide array data

• Zhijin Wu
• Rafael A Irizarry

Response to Preprocessing of oligonucleotide array data

• Li Zhang
• Chunlei Wu
• Kevin R Coombes

Biotechnology as religion

• Leigh Turner

Diversifying in biotech

• Tom Jacobs

Show me the money

• Laura DeFrancesco

Public biotechnology 2003—the numbers

• Riku Lähteenmäki
• Monya Baker

Industrial biotechnology—a chance at redemption

• Stephan Herrera

An image worth a thousand lives?

• Lisa A Hammond
• Sean X Cavanaugh
• Charles R Thomas Jr

Genome sequence of an omnipotent fungus

• Tuula T Teeri

From alpha to omega—producing essential fatty acids in plants

• Allan G Green

The best of both worlds in plant protection

• Holger Bohlmann

A mightier mouse with human adaptive immunity

• Marie H Kosco-Vilbois

Research Notes

Apomixis technology development—virgin births in farmers' fields?

• Charles Spillane
• Mark D Curtis
• Ueli Grossniklaus

Serial bull cloning by somatic cell nuclear transfer

• Chikara Kubota
• X Cindy Tian
• Xiangzhong Yang

Genome sequence of the lignocellulose degrading fungus Phanerochaete chrysosporium strain RP78

• Diego Martinez
• Luis F Larrondo
• Daniel Rokhsar

Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors

• Peter M Smith-Jones
• David B Solit
• Steven M Larson

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation

• Ralph Brandenberger
• Henry Wei
• Lawrence W Stanton

Chemical screening by mass spectrometry to identify inhibitors of anthrax lethal factor

• Dal-Hee Min
• Wei-Jen Tang
• Milan Mrksich

Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues

• Gerold Schmitt-Ulms
• Kirk Hansen
• Michael A Baldwin

Fusion proteins comprising a Fusarium-specific antibody linked to antifungal peptides protect plants against a fungal pathogen

• Dieter Peschen
• He-Ping Li
• Yu-Cai Liao

Production of very long chain polyunsaturated omega-3 and omega-6 fatty acids in plants

• Baoxiu Qi
• Tom Fraser
• Colin M Lazarus

Engineering plants with increased levels of the antioxidant chlorogenic acid

• Ricarda Niggeweg
• Anthony J Michael
• Cathie Martin

Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution

• Farid J Ghadessy
• Nicola Ramsay
• Philipp Holliger

Erratum: Erbitux diagnostic latest adjunct to cancer therapy

• Peter Mitchell

Correction: Corrigendum: Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide–based retroviral vector

• Andrea L Szymczak
• Creg J Workman
• Dario AA Vignali

Correction: Corrigendum: The potential environmental impact of engineered nanomaterials

• Vicki L Colvin

Addendum: Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide–based retroviral vector

• Andrea L Szymczak
• Creg J Workman
• Dario AA Vignali

Managing innovation: university-industry partnerships and the licensing of the Harvard mouse

• Sasha Blaug
• Colleen Chien
• Michael J Shuster

Recent patent applications related to drug delivery

People

Antibodies and Sample prep

Computer security in academia—a potential roadblock to distributed annotation of the human genome

• Dov Greenbaum
• Shawn M Douglas
• Mark Gerstein

Bio-ontologies—fast and furious

• Judith Blake

A bean counter's take on human resources

• Paul Watson