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Managing innovation: university-industry partnerships and the licensing of the Harvard mouse

Nature Biotechnology volume 22, pages 761–763 (2004)Cite this article

DuPont's Oncomouse patent licensing program continues to cause a stir in academia and industry.

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References

  1. Study on research universities funded by the European Commission (http://ed.sjtu.edu.cn/rank/rank-2003.mht).

  2. Association of University Technology Managers survey (2000) and Working Together, Creating Knowledge, The University-Industry Research Collaboration Initiative (2001).

  3. Campbell, E. et al. Health Affairs 23, 64–76 (2004).

    Article  Google Scholar 

  4. Hall, Z.W. & Scott, C. Science 291, 553 (2001).

    Article  CAS  Google Scholar 

  5. Edwards, M.G. et al., Nat. Biotechnol. 21, 618–624 (2003).

    Article  CAS  Google Scholar 

  6. Associated Press. Uproar over mighty mouse (8 November, 2003).

  7. Marshall, E. Science 296, 1212–1213 (2002).

    Article  CAS  Google Scholar 

  8. Smaglik, P. Nature 403, 350 (2000).

    Article  CAS  Google Scholar 

  9. Memorandum of Understanding between E.I. DuPont de Nemours and Company and Public Health Service (MOU) (http://ott.od.nih.gov/textonly/oncomous.htm).

  10. Gordon, J.W. & Ruddle, F.H. Science 214, 1244–1246 (1981).

    Article  CAS  Google Scholar 

  11. Palmiter and Brinster reported in the scientific literature the first cancer prone transgenic mouse 4 months earlier than Leder and days before the filing of Harvard's patent. Brinster R.L. et al. Cell 37, 367–379 (1984).

    Article  CAS  Google Scholar 

  12. Stewart, T.A., Pattengale, P.K. & Leder, P. Cell 38, 627–637 (1984).

    Article  CAS  Google Scholar 

  13. US Patent 4,736,866.

  14. US Patent 5,925,803.

  15. Grants 1Z01HD000074-4 through 1Z01HD000074-11, awarded by the National Institute of Child Health and Human Development (http://crisp.cit.nih.gov/).

  16. Grossblatt, N. (ed.). Sharing Laboratory Resources: Genetically Altered Mice. Summary of a Workshop Held at the National Academy of Sciences, March 23–24, 1993 by National Research Council, Ch. 4, 21–23 (National Academy Press, Washington, DC, 1994).

  17. Melbourne Herald Sun, Australia. p. 52 (8 November 2003).

  18. Lamb, C. Sacramento Business Journal (3 November 2003).

    Google Scholar 

  19. Heller, A. & Eisenberg, R.S. Science 280, 698–701 (1998).

    Article  CAS  Google Scholar 

  20. See MOU, supra note 9, at Section (1).

  21. See, for example, Cook, G. The Boston Globe (31 May 2002).

  22. See, for example, Policy Guidelines Governing Openness and Freedom to Publish (http://www.spo.berkeley.edu/Policy/ucmemos/publish.html), and Principles Regarding Rights to Future Research Results in University Agreements with External Parties (http://www.ucop.edu/ott/preamble.pdf).

  23. See Memo Operating Guidance on Industry-University Relationships, No. 89-20 (6 June 1989) (http://www.ucop.edu/raohome/cgmemos/89-20.html).

  24. Lawler, A. Science 299, 330–333 (2003).

    Article  CAS  Google Scholar 

  25. AUTM 2000, 2001 and 2002 studies (http://www.autm.net/).

  26. See NIH letter to UC (http://206.151.87.67/docs/OncoMouseDuPont.doc).

  27. Madey v. Duke, 307 F.3d 1351 (Fed. Cir. 2002).

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Author notes

  1. Sasha Blaug and Colleen Chien: Indicates joint first-authorship.

Authors and Affiliations

  1. Fenwick & West LLP, Silicon Valley Center, 801 California Street, Mountain View, 94041, California, USA

    Sasha Blaug

  2. Fenwick & West LLP, 275 Battery Street, San Francisco, 94111, California, USA

    Colleen Chien & Michael J Shuster

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  1. Sasha Blaug
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  2. Colleen Chien
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  3. Michael J Shuster
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Blaug, S., Chien, C. & Shuster, M. Managing innovation: university-industry partnerships and the licensing of the Harvard mouse. Nat Biotechnol 22, 761–763 (2004). https://doi.org/10.1038/nbt0604-761

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