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| Opinion |  Top |
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| Editorials |
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"Bottom-up" bioremediation p393
doi:10.1038/nbt0597-393a
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IP's shifting sands p393
doi:10.1038/nbt0597-393b
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The collective bargain p393
doi:10.1038/nbt0597-393c
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| Commentary |
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Finding a vocabulary for the extrascientific significance of technology p394
Edward S. Golub
doi:10.1038/nbt0597-394
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(177K)
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Novartis' new labeling policy creates confusion p395
Russ Hoyle
doi:10.1038/nbt0597-395
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(186K)
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Epigenesis and Complexity: Should you hire an epistemologist? p396
William Bains
doi:10.1038/nbt0597-396
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(143K)
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| In Brief | Top |
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| Business and Regulatory News |
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Business & Regulatory News pp397 - 399
doi:10.1038/nbt0597-397
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| Research News |
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Research News p400
doi:10.1038/nbt0597-400
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(383K)
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| This Month in Biotechnology |
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This Month In Nature Biotechnology p401
doi:10.1038/nbt0597-401
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(360K)
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| Analysis | Top |
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| Business and Regulatory News |
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Appeal court grants Genentech's growth market to Novo Nordisk p403
Jim Kling
doi:10.1038/nbt0597-403a
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(147K)
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Novartis find sparks new GABA drug search pp403 - 404
Alex Eccleston
doi:10.1038/nbt0597-403b
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(291K)
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FDA rapidly approves HIV protease inhibitors for children p404
Jeffrey L. Fox
doi:10.1038/nbt0597-404
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(159K)
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New clot busters threaten Genentech's tPA p405
Sylvia Davidson
doi:10.1038/nbt0597-405
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(200K)
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Litigation escalates for patents on a chip p406
William Bains
doi:10.1038/nbt0597-406a
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(128K)
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Bioethicists ruminate separately on clones, gene 'enhancements' pp406 - 407
Jeffrey L. Fox
doi:10.1038/nbt0597-406b
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(338K)
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EPA seeks refuge from Bt resistance p409
Jeffrey L Fox
doi:10.1038/nbt0597-409
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(215K)
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Biogen wins Euro MS approval, but loses patents p410
Vicki Brower
doi:10.1038/nbt0597-410
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(98K)
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The FDA "reinvents" human cell and tissue regulations p411
Vicki Brower
doi:10.1038/nbt0597-411
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(269K)
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Public biotechnology companies earn $12.4billion, spend $5.2 billion pp412 - 413
John Hodgson
& Riku Lähteenmäki
doi:10.1038/nbt0597-412
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(679K)
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| Research News |
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Clearing the way for ribozymes pp414 - 415
John M. Burke
doi:10.1038/nbt0597-414
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(297K)
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Bacterial biocatalysis: Stealing a page from nature's book pp415 - 416
Lawrence P. Wackett
doi:10.1038/nbt0597-415
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(263K)
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A new lease on life for transgenic livestock pp416 - 417
Robert J. Wall
doi:10.1038/nbt0597-416
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(492K)
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From weeds spring eternal flowers p418
Mondher Bouzayen
& Jean-Claude Pech
doi:10.1038/nbt0597-418
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(306K)
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Sweet science: Overexpression of monellin in yeast pp419 - 420
Robert Dansby
doi:10.1038/nbt0597-419
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(649K)
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Immunosensors: The next generation p421
Anthony PF Turner
doi:10.1038/nbt0597-421
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(164K)
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| Feature | Top |
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Genetic testing: The problems and the promise pp422 - 426
Charis Eng
& Jan Vijg
doi:10.1038/nbt0597-422
Abstract + references | PDF
(2,220K)
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| Research Review | Top |
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DNA enzymes pp427 - 431
Ronald R. Breaker
doi:10.1038/nbt0597-427
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(635K)
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| Research Articles | Top |
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Efficient hammerhead ribozyme and antisense RNA targeting in a slow ribosome Escherichia colimutant pp432 - 435
Hui Chen, Gerardo Ferbeyre
& Robert Cedergren
doi:10.1038/nbt0597-432
Abstract + references | PDF
(578K)
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Molecular evolution of an arsenate detoxification pathway by DNA shuffling pp436 - 438
Andreas Crameri, Glenn Dawes, Emilio Rodriguez Jr., Simon Silver
& Willem P.C. Stemmer
doi:10.1038/nbt0597-436
Abstract + references | PDF
(499K)
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Chimeric proteins can exceed the sum of their parts: Implications for evolution and protein design pp439 - 443
Robert K. Campbell, Elizabeth R. Bergert, Yanhong Wang, John C. Morris
& William R. Moyle
doi:10.1038/nbt0597-439
Abstract + references | PDF
(559K)
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A dominant mutant receptor from Arabidopsis confers ethylene insensitivity in heterologous plants pp444 - 447
Jack Q. Wilkinson, Michael B. Lanahan, David G. Clark, Anthony B. Bleecker, Caren Chang, Elliot M. Meyerowitz
& Harry J. Klee
doi:10.1038/nbt0597-444
Abstract + references | PDF
(760K)
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Metabolic fluxes in riboflavin-producing Bacillus subtilis pp448 - 452
Uwe Sauer, Vassily Hatzimanikatis, James E. Bailey, Michel Hochuli, Thomas Szyperski
& Kurt Wüthrich
doi:10.1038/nbt0597-448
Abstract + references | PDF
(692K)
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High-level expression of a sweet protein, monellin, in the food yeast Candida utilis pp453 - 457
Keiji Kondo, Yutaka Miura, Hidetaka Sone, Kazuo Kobayashi
& Hiroshi lijima
doi:10.1038/nbt0597-453
Abstract + references | PDF
(809K)
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Selective production of transgenic mice using green fluorescent protein as a marker pp458 - 461
Tatsuyuki Takada, Keiko lida, Takeo Awaji, Kazumi Itoh, Riichi Takahashi, Akiko Shibui, Kenichi Yoshida, Sumio Sugano
& Gozoh Tsujimoto
doi:10.1038/nbt0597-458
Abstract + references | PDF
(730K)
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In vitro and in vivo gene delivery mediated by a synthetic polycationic amino polymer pp462 - 466
Corey K. Goldman, Liliana Soroceanu, Natalie Smith, G. Yancey Gillespie, Walter Shaw, Steve Burgess, Guadalupe Bilbao
& David T. Curiel
doi:10.1038/nbt0597-462
Abstract + references | PDF
(705K)
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Real-time measurements of corticosteroids in conscious animals using an antibody-based electrode pp467 - 471
Christian J. Cook
doi:10.1038/nbt0597-467
Abstract + references | PDF
(753K)
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| Resources | Top |
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| Patents |
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Protecting the patentability of your collaborative research pp472 - 473
Virginia C. Bennett
& Sorojini J. Biswas
doi:10.1038/nbt0597-472
Abstract + references | PDF
(276K)
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Recent patent applications in the area of sequencing p474
doi:10.1038/nbt0597-474
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(251K)
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| WWW Guide |
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World Wide Web sites in biotechnology p475
Robert Skikorski
& Richard Peters
doi:10.1038/nbt0597-475
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(188K)
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| People |
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People pp476 - 477
doi:10.1038/nbt0597-476
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(412K)
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| New Products |
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New Products p478
doi:10.1038/nbt0597-478
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(184K)
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| Industry Trends |
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The carbohydrate-based drug industry pp479 - 480
Aris Persidis
doi:10.1038/nbt0597-479
Abstract + references | PDF
(415K)
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