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HIV

Cure by killing

Nature volume 528, pages 198–199 (2015)Cite this article

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Two bi-specific protein constructs have been designed that direct the body's T cells to kill HIV-infected cells. The feat provides a step on the path to removing the latent virus reservoir that persists in patients on antiretroviral therapy.

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Figure 1: Bi-specific constructs.

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References

  1. Sung, J. A. M. et al. J. Clin. Invest. 125, 4077–4090 (2015).

    Article  Google Scholar 

  2. Pegu, A. et al. Nature Commun. 6, 8447 (2015).

    Article  ADS  CAS  Google Scholar 

  3. Archin, N. M. et al. Nature 487, 482–485 (2012).

    Article  ADS  CAS  Google Scholar 

  4. Elliott, J. H. et al. PLoS Pathog. 10, e1004473 (2014).

    Article  Google Scholar 

  5. Rasmussen, T. A. et al. Lancet HIV 1, e13–e21 (2014).

    Article  Google Scholar 

  6. Deng, K. et al. Nature 517, 381–385 (2015).

    Article  ADS  CAS  Google Scholar 

  7. Berg, J. et al. Proc. Natl Acad. Sci. USA 88, 4723–4727 (1991).

    Article  ADS  CAS  Google Scholar 

  8. Traunecker, A., Lanzavecchia, A. & Karjalainen, K. EMBO J. 10, 3655–3659 (1991).

    Article  CAS  Google Scholar 

  9. Bargou, R. et al. Science 321, 974–977 (2008).

    Article  ADS  CAS  Google Scholar 

  10. Richman, D. D. et al. Science 323, 1304–1307 (2009).

    Article  ADS  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Douglas D. Richman is at the Center for AIDS Research, University of California San Diego, La Jolla, California 92093-0679, USA, and at the Veteran Affairs San Diego Healthcare System, San Diego.,

    Douglas D. Richman

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  1. Douglas D. Richman
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Correspondence to Douglas D. Richman.

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Richman, D. Cure by killing. Nature 528, 198–199 (2015). https://doi.org/10.1038/nature16321

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