Table of contents


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Opinion

Seedless in Seattle? p329

When negotiators gather in Seattle this weekend for the ministerial meeting of the World Trade Organization, the future of genetically modified crops will be high on their agenda.

doi:10.1038/46344


A bioethics dilemma for Germany p329

Debates on the ethics of biomedical research must find a way to combine breadth of vision with a practical timescale.

doi:10.1038/46346


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News

German bioethics inquiry 'could hold up essential changes' p331

Quirin Schiermeier

doi:10.1038/46348


'It's a G': the one-billionth nucleotide p331

David Dickson and Colin Macilwain

doi:10.1038/46351


Israel urged to set up labs to carry out military research p332

Haim Watzman

doi:10.1038/46354


Concern at cheap AIDS drug fears p332

Michael Cherry

doi:10.1038/46356


Praise greets accuracy of Leonid prediction p333

Tony Reichhardt

doi:10.1038/46358


Brookhaven leak reactor to close p333

Colin Macilwain

doi:10.1038/46361


Science lobby 'ecstatic' after triumph in NIH budget battle p334

Meredith Wadman

doi:10.1038/46365


Hughes institute unveils top team p334

Colin Macilwain

doi:10.1038/46367


Busquin plans white paper to integrate European research p335

Keith Nuttall

doi:10.1038/46370


Genentech pays $200m over growth hormone 'theft' p335

Rex Dalton and Quirin Schiermeier

doi:10.1038/46372


China on verge of putting man into space... p336

Tian Xuewen

doi:10.1038/46374


...as a new failed satellite launch embarrasses Japan p336

Asako Saegusa

doi:10.1038/46376


Gender discrimination 'undermines science' p337

Natasha Loder

doi:10.1038/46379


news in brief p338

doi:10.1038/46383


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Briefings

Access issues may determine whether agri-biotech will help the world's poor p341

Despite doubts in the West about GM crops, many developing countries are keen to exploit them — if they are allowed to do so at an affordable price.

Colin Macilwain

doi:10.1038/46385


India intends to reap the full commercial benefits p342

Licensing problems are slowing the adoption of GM crops in India

K. S. Jayaraman

doi:10.1038/46391


Agri-biotech information sources p344

doi:10.1038/46398


Smugglers aim to circumvent GM court ban in Brazil p344

Brazilian farmers are fighting back against legal barriers of GM crops.

Ricardo Bonalume Neto

doi:10.1038/46400


Academies link to map scientific priorities for meeting real needs p345

David Dickson

doi:10.1038/46403


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Correspondence

Promoting a standard nomenclature for genes and proteins p347

Julia White, Hester Wain, Elspeth Bruford and Sue Povey

doi:10.1038/46405


Sequencing challenge p347

Lois J. Maltais and Ian Jackson

doi:10.1038/46407


What's in a name? p347

Tony Smith

doi:10.1038/46409


Cooperative efforts around Lake Tahoe p348

Stephen G. Wells, James S. Coleman, Joseph N. Crowley and Kenneth W. Hunter, Jr

doi:10.1038/46411


Precautionary approach to risk assessment p348

Alister Scott, Andy Stirling, Nick Mabey, Frans Berkhout, Chris Williams, Chris Rose, Michael Jacobs, Robin Grove-White, Ian Scoones and Melissa Leach

doi:10.1038/46413


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Book Reviews

Mastering the art of the skies p349

The observations of Virgil and of a Quaker chemist converge on canvas.

Euan Nisbet reviews John Constable's Skies: A Fusion of Art and Science by John E. Thornes

doi:10.1038/46415


Personal views of an impersonal world p350

Howard P. Segal reviews Meaning in Technology by Arnold Pacey

doi:10.1038/46419


A friend of one's own p351

Paul L. Harris reviews Imaginary Companions and the Children Who Create them by Marjorie Taylor

doi:10.1038/46421


Sniffing the world of olfaction p351

Vincent Dusastre reviews Electronic Noses: Principles and Applications by Julian W. Gardner and Philip N. Bartlett

doi:10.1038/46424


Cellular variations p352

doi:10.1038/46426


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Millennium Essay

Two millennia of animal spirits p353

An ancient theory about nerves proved surprisingly hard to dislodge.

Ian Glynn

doi:10.1038/46428


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Futures

Emortality — at last! p355

Ali Zaman's recipe for eternal life will set us free.

Brian Stableford

doi:10.1038/46431


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News and Views

Plug-in quantum software p357

Some quantum states are hard to create and maintain, but are a valuable resource for computing. Twenty-first century entrepreneurs could make a fortune selling disposable quantum states.

John Preskill

doi:10.1038/46434


Botany: The family tree flowers p358

Paul Kenrick

doi:10.1038/46437


Astronomy: Clouds from near and far p359

W. Butler Burton and Robert Braun

doi:10.1038/46440


Functional genomics: What do yeast proteins do? p362

Philip Hieter

doi:10.1038/46443


Ocean biogeochemistry: Sulphur in the mix p363

Ronald P. Kiene

doi:10.1038/46446


100 and 50 years ago p363

doi:10.1038/46448


Phylogenomics: Ancestral primate viewed p365

Stephen J. O'Brien and Roscoe Stanyon

doi:10.1038/46450


Ecology: Competition and coexistence p366

Ulrich Sommer

doi:10.1038/46453


Daedalus: Internal ecology p367

David Jones

doi:10.1038/46455


Obituary: Charles M. Steinberg (1932–99) p368

Jack von Borstel and John Cairns

doi:10.1038/46457


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Brief Communications

Feeding by mandibular raking in a snake p369

The tiny threadsnake has a unique way of devouring ants before they can strike back.

N. J. Kley and E. L. Brainerd

doi:10.1038/46460


Genetic techniques: A universal marker for transgenic insects p370

Andreas J. Berghammer, Martin Klingler and Ernst A. Wimmer

doi:10.1038/46463


Development: Ubiquitin tag for sperm mitochondria p371

Peter Sutovsky, Ricardo D. Moreno, João Ramalho-Santos, Tanja Dominko, Calvin Simerly and Gerald Schatten

doi:10.1038/46466


Oceanography: Iron, nitrogen and phosphorus in the ocean p372

John J. Cullen

doi:10.1038/46469


reply: Oceanography: Iron, nitrogen and phosphorus in the ocean p372

Toby Tyrrell

doi:10.1038/46472


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Progress

Active site-directed protein regulation p373

Bostjan Kobe and Bruce E. Kemp

doi:10.1038/46478


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Article

Structure of fumarate reductase from Wolinella succinogenes at 2.2 Å resolution p377

C. Roy D. Lancaster, Achim Kröger, Manfred Auer and Hartmut Michel

doi:10.1038/46483


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Letters to Nature

Discovery of molecular hydrogen in a high-velocity cloud of the Galactic halo p386

P. Richter, K. S. de Boer, H. Widmann, N. Kappelmann, W. Gringel, M. Grewing and J. Barnstedt

doi:10.1038/46492


Accretion of low-metallicity gas by the Milky Way p388

B. P. Wakker, J. C. Howk, B. D. Savage, H. van Woerden, S. L. Tufte, U. J. Schwarz, R. Benjamin, R. J. Reynolds, R. F. Peletier and P. M. W. Kalberla

doi:10.1038/46498


Demonstrating the viability of universal quantum computation using teleportation and single-qubit operations p390

Daniel Gottesman and Isaac L. Chuang

doi:10.1038/46503


Coupled synthesis and self-assembly of nanoparticles to give structures with controlled organization p393

Mei Li, Heimo Schnablegger and Stephen Mann

doi:10.1038/46509


Role of vertical mixing in controlling the oceanic production of dimethyl sulphide p396

Rafel Simó and Carlos Pedrós-Alió

doi:10.1038/46516


The effect of climate change on ozone depletion through changes in stratospheric water vapour p399

Daniel B. Kirk-Davidoff, Eric J. Hintsa, James G. Anderson and David W. Keith

doi:10.1038/46521


Angiosperm phylogeny inferred from multiple genes as a tool for comparative biology p402

Pamela S. Soltis, Douglas E. Soltis and Mark W. Chase

doi:10.1038/46528


The earliest angiosperms: evidence from mitochondrial, plastid and nuclear genomes p404

Yin-Long Qiu, Jungho Lee, Fabiana Bernasconi-Quadroni, Douglas E. Soltis, Pamela S. Soltis, Michael Zanis, Elizabeth A. Zimmer, Zhiduan Chen, Vincent Savolainen and Mark W. Chase

doi:10.1038/46536


Biodiversity of plankton by species oscillations and chaos p407

Jef Huisman and Franz J. Weissing

doi:10.1038/46540


The dynamics of chromosome evolution in birds and mammals p411

David W. Burt, Charlotte Bruley, Ian C. Dunn, Cheryl T. Jones, Anne Ramage, Andy S. Law, David R. Morrice, Ian R. Paton, Jacqueline Smith, Dawn Windsor, Alexei Sazanov, Ruedi Fries and David Waddington

doi:10.1038/46555


Large-scale analysis of the yeast genome by transposon tagging and gene disruption p413

Petra Ross-Macdonald, Paulo S. R. Coelho, Terry Roemer, Seema Agarwal, Anuj Kumar, Ronald Jansen, Kei-Hoi Cheung, Amy Sheehan, Dawn Symoniatis, Lara Umansky, Matthew Heidtman, F. Kenneth Nelson, Hiroshi Iwasaki, Karl Hager, Mark Gerstein, Perry Miller, G. Shirleen Roeder and Michael Snyder

doi:10.1038/46558


Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast p418

John J. Wyrick, Frank C. P. Holstege, Ezra G. Jennings, Helen C. Causton, David Shore, Michael Grunstein, Eric S. Lander and Richard A. Young

doi:10.1038/46567


LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite p421

N. Toni, P.-A. Buchs, I. Nikonenko, C. R. Bron and D. Muller

doi:10.1038/46574


Conserved regulation of proximodistal limb axis development by Meis1/Hth p425

Nadia Mercader, Esther Leonardo, Natalia Azpiazu, Antonio Serrano, Ginés Morata, Carlos Martínez-A and Miguel Torres

doi:10.1038/46580


CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid p429

Roberto Weigert, Maria Giuseppina Silletta, Stefania Spanò, Gabriele Turacchio, Claudia Cericola, Antonino Colanzi, Silvia Senatore, Raffaella Mancini, Elena V. Polishchuk, Mario Salmona, Francesco Facchiano, Koert N. J. Burger, Alexander Mironov, Alberto Luini and Daniela Corda

doi:10.1038/46587


Crystal structures of the membrane-binding C2 domain of human coagulation factor V p434

Sandra Macedo-Ribeiro, Wolfram Bode, Robert Huber, Mary Ann Quinn-Allen, Suhng Wook Kim, Thomas L. Ortel, Gleb P. Bourenkov, Hans D. Bartunik, Milton T. Stubbs, William H. Kane and Pablo Fuentes-Prior

doi:10.1038/46594


Structure of the C2 domain of human factor VIII at 1.5 Å resolution p439

Kathleen P. Pratt, Betty W. Shen, Kazuya Takeshima, Earl W. Davie, Kazuo Fujikawa and Barry L. Stoddard

doi:10.1038/46601


addendum: Energetic constraints on the diet of terrestrial carnivores p442

Chris Carbone, Georgina M. Mace, S. Craig Roberts and David W. Macdonald

doi:10.1038/46607


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New on the Market

Please release me p443

This software update includes releases of old favourites like SigmaPlot.

doi:10.1038/46609


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