Opinion

Technology transfer requires an entrepreneurial academia p1

Attempts to replicate the recent success of US technology transfer need to focus on the toughest elements of the problem: the availability of venture capital and the structure of the university system.

doi:10.1038/43236

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Changing Nature (cont.) p1

This issue includes some enhancements to Nature's subliminal impact.

doi:10.1038/43238

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News

Japan acts to speed technology transfer from universities p3

Asako Saegusa

doi:10.1038/43240

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Crop trials seek to allay public fears p3

Asako Saegusa

doi:10.1038/43243

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Cash bonuses won't stop brain drain, say Canadian academics p4

David Spurgeon

doi:10.1038/43245

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Call for governments to back development of AIDS vaccine p4

David Dickson

doi:10.1038/43248

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Go-ahead for San Andreas drilling project... p5

Rex Dalton

doi:10.1038/43251

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... and more money for the Earth sciences in Germany p5

Quirin Schiermeier

doi:10.1038/43254

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Funding problems threaten Middle East's synchrotron p6

Heather McCabe

doi:10.1038/43256

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E-Biomed to be launched as a repository for research p6

Colin Macilwain

doi:10.1038/43259

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Pollard resigns as president of Salk p6

Rex Dalton

doi:10.1038/43261

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News Analysis

US faces increasing demand for funds to replace ageing equipment p7

Despite moves to boost funding, US biologists are struggling to pay for the instruments they need to remain competitive.

Meredith Wadman

doi:10.1038/43263

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News in Brief p8

doi:10.1038/43267

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Correspondence

Swift action needed to close the skills gap in bioinformatics p10

Marlie MacLean and Colin Miles

doi:10.1038/43269

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France is still in the running on genomics p10

François Gros

doi:10.1038/43271

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Japan's researchers could face more red tape p10

Kazuhiko Kobayashi

doi:10.1038/43273

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New Journals

Seeing the wood for the trees p11

New journals are welcomed in rapidly changing disciplines, but — as Internet resources grow — many reviewers say we'd be better off saving the paper.

Mark Saffman reviews Journal of Optics A: Pure and Applied Optics and Journal of Optics B: Quantum and Semiclassical Optics

doi:10.1038/43275

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By the people, for the people p11

Peter McGregor reviews Evolutionary Ecology Research

doi:10.1038/43278

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Pulling the wings off flies p12

T.S. Collett reviews Animal Cognition

doi:10.1038/43280

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Smell, taste and other hot topics p12

Tristram D. Wyatt reviews Chemoecology

doi:10.1038/43283

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Complex issues in a specialist field p12

Eugene Stanley reviews Advances in Complex Systems

doi:10.1038/43285

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Quick work but variable quality p13

Martin A. Giese reviews Pattern Analysis and Applications

doi:10.1038/43287

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New developments in an old discipline p13

Dante Gatteschi reviews Inorganic Chemistry Communications

doi:10.1038/43290

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Materials with added value p14

Robert W. Cahn reviews Journal of Electroceramics

doi:10.1038/43292

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Earthquakes – the grand and the gritty p14

George Helffrich reviews Journal of Seismology

doi:10.1038/43294

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Bugs, glorious bugs p14

Peter H. Williams reviews Current Opinion in Microbiology

doi:10.1038/43297

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Computers and the human brain p15

Amanda Parker reviews CyberPsychology & Behavior

doi:10.1038/43299

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Testing the market in search of a niche p15

Peter Harper reviews Genetic Testing

doi:10.1038/43302

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Evolving discipline finds a forum p16

Gema Frühbeck reviews Nutritional Neuroscience and Public Health Nutrition

doi:10.1038/43304

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Birds unlimited p16

Juha Merilä reviews BWP Update: The Journal of Birds of the Western Palearctic

doi:10.1038/43306

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Depends how much time you've got p16

David P. Pope reviews Mechanics of Time-Dependent Materials

doi:10.1038/43308

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Working together for the Earth p17

David G. Victor reviews Environmental Science & Policy

doi:10.1038/43311

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Modern questions in a traditional form p17

W.F. Bynum reviews Studies in History and Philosophy of Biological and Biomedical Sciences

doi:10.1038/43313

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New shoots to replace the old? p18

Ortrun Mittelsten Scheid reviews Current Opinion in Plant Biology

doi:10.1038/43315

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Grains of wisdom unite two disciplines p18

Dov Levine reviews Granular Matter

doi:10.1038/43318

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Millennium Essay

Last days in Arcadia p19

The genetic code and Francis Crick shared a memorable birthday party.

John Cairns

doi:10.1038/43320

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News and Views

Electrons seen in orbit p21

The classic textbook shape of electron orbitals has now been directly observed. As well as confirming the established theory, this work may be a first step to understanding high-temperature superconductivity.

Colin J. Humphreys

doi:10.1038/43323

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Ecology: Bite the mother, fight the daughter p22

Erkki Haukioja

doi:10.1038/43327

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Random fluctuations: Unsolved problems of noise p23

Peter V. E. McClintock

doi:10.1038/43331

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Neurobiology: Young receptors make smart mice p25

T. V. P. Bliss

doi:10.1038/43333

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Dark matter: Lumpy haloes spin faster p27

James Binney

doi:10.1038/43336

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100 and 50 years ago p27

doi:10.1038/43338

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Protein unfolding: Trapped in the act p29

Tania A. Baker

doi:10.1038/43341

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Protein folding: Where do the electrons go? p30

Rudi Glockshuber

doi:10.1038/43344

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Earth science: Does global cooling reduce relief? p31

Eric Small

doi:10.1038/43348

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Astronomy: Chandra opens its eyes p32

Sarah Tomlin

doi:10.1038/43351

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Apoptosis: Akt is more than just a Bad kinase p33

Asim Khwaja

doi:10.1038/43354

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Daedalus: Slip through the water p34

David Jones

doi:10.1038/43358

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Brief Communications

Why cars in the next lane seem to go faster p35

The temptation to change lanes on a motorway may be prompted by an illusion.

Donald A. Redelmeier and Robert J. Tibshirani

doi:10.1038/43360

First paragraph | Full Text | PDF (124K)

Rare-earth metals: Is gadolinium really ferromagnetic? p35

J.M.D. Coey, V. Skumryev and K. Gallagher

doi:10.1038/43363

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Physiology: Warm feet promote the rapid onset of sleep p36

Kurt Kräuchi, Christian Cajochen, Esther Werth and Anna Wirz-Justice

doi:10.1038/43366

First paragraph | Full Text | PDF (180K)

Biological motors: Connecting stalks in V-type ATPase p37

E.J. Boekema, J.F.L. van Breemen, A. Brisson, T. Ubbink-Kok, W.N. Konings and J.S. Lolkema

doi:10.1038/43369

First paragraph | Full Text | PDF (151K)

Insect behaviour: Evolutionary origins of bee dances p38

A. Dornhaus and L. Chittka

doi:10.1038/43372

First paragraph | Full Text | PDF (72K)

Article

Geomorphic limits to climate-induced increases in topographic relief p39

Kelin X Whipple, Eric Kirby and Simon H. Brocklehurst

doi:10.1038/43375

Abstract | Full Text | PDF (206K)

See also: News and Views by Small

Letters to Nature

Continuous heating of a giant X-ray flare on Algol p44

J. H. M. M. Schmitt and F. Favata

doi:10.1038/43389

First paragraph | Full Text | PDF (330K)

Conical dislocations in crumpling p46

Enrique Cerda, Sahraoui Chaieb, Francisco Melo and L. Mahadevan

doi:10.1038/43395

First paragraph | Full Text | PDF (415K)

Direct observation of d-orbital holes and Cu–Cu bonding in Cu₂O p49

J. M. Zuo, M. Kim, M. O'Keeffe and J. C. H. Spence

doi:10.1038/43403

First paragraph | Full Text | PDF (486K)

See also: News and Views by Humphreys

Discerning vibronic molecular dynamics using time-resolved photoelectron spectroscopy p52

Valérie Blanchet, Marek Z. Zgierski, Tamar Seideman and Albert Stolow

doi:10.1038/43410

First paragraph | Full Text | PDF (316K)

Small-bandgap endohedral metallofullerenes in high yield and purity p55

S. Stevenson, G. Rice, T. Glass, K. Harich, F. Cromer, M. R. Jordan, J. Craft, E. Hadju, R. Bible, M. M. Olmstead, K. Maitra, A. J. Fisher, A. L. Balch and H. C. Dorn

doi:10.1038/43415

First paragraph | Full Text | PDF (242K) | Supplementary information

A Middle Jurassic mammal from Madagascar p57

John J. Flynn, J. Michael Parrish, Berthe Rakotosamimanana, William F. Simpson and André R. Wyss

doi:10.1038/43420

First paragraph | Full Text | PDF (512K)

Transgenerational induction of defences in animals and plants p60

Anurag A. Agrawal, Christian Laforsch and Ralph Tollrian

doi:10.1038/43425

First paragraph | Full Text | PDF (175K)

See also: Letter by Agrawal et al.

Genetic enhancement of learning and memory in mice p63

Ya-Ping Tang, Eiji Shimizu, Gilles R. Dube, Claire Rampon, Geoffrey A. Kerchner, Min Zhuo, Guosong Liu and Joe Z. Tsien

doi:10.1038/43432

First paragraph | Full Text | PDF (386K) | Supplementary information

See also: News and Views by Bliss

Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1 p69

Veit H. Höpker, Derryck Shewan, Marc Tessier-Lavigne, Mu-ming Poo and Christine Holt

doi:10.1038/43441

First paragraph | Full Text | PDF (356K)

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy p73

Iichiro Shimomura, Robert E. Hammer, Shinji Ikemoto, Michael S. Brown and Joseph L. Goldstein

doi:10.1038/43448

First paragraph | Full Text | PDF (799K)

Rapid on/off cycling of cytokine production by virus-specific CD8⁺ T cells p76

Mark K. Slifka, Fernando Rodriguez and J. Lindsay Whitton

doi:10.1038/43454

First paragraph | Full Text | PDF (1,209K) | Supplementary information

Cell transformation by the superoxide-generating oxidase Mox1 p79

Young-Ah Suh, Rebecca S. Arnold, Bernard Lassegue, Jing Shi, Xiangxi Xu, Dan Sorescu, Andrew B. Chung, Kathy K. Griendling and J. David Lambeth

doi:10.1038/43459

First paragraph | Full Text | PDF (257K)

NF-B activation by tumour necrosis factor requires the Akt serine–threonine kinase p82

Osman Nidai Ozes, Lindsey D. Mayo, Jason A. Gustin, Susan R. Pfeffer, Lawrence M. Pfeffer and David B. Donner

doi:10.1038/43466

First paragraph | Full Text | PDF (240K)

See also: News and Views by Khwaja

NF-B is a target of AKT in anti-apoptotic PDGF signalling p86

Julia A. Romashkova and Sergei S. Makarov

doi:10.1038/43474

First paragraph | Full Text | PDF (308K)

See also: News and Views by Khwaja

Global unfolding of a substrate protein by the Hsp100 chaperone ClpA p90

Eilika U. Weber-Ban, Brian G. Reid, Andrew D. Miranker and Arthur L. Horwich

doi:10.1038/43481

First paragraph | Full Text | PDF (206K)

See also: News and Views by Baker

Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide p93

Jeannie R. Rojas, Raymond C. Trievel, Jianxin Zhou, Yi Mo, Xinmin Li, Shelley L. Berger, C. David Allis and Ronen Marmorstein

doi:10.1038/43487

First paragraph | Full Text | PDF (443K)