Opinion

Uncertainty and naivety in Germany's science politics p183

The SPD and Green coalition that governs Germany has made notable progress and demonstrated flexibility in the process. But the Greens' lack of expertise needs redressing if good science is to get the support it deserves.

doi:10.1038/16503

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Arima ascendant p183

The choice of the new head of Japan's education ministry and Science and Technology Agency is to be applauded.

doi:10.1038/16505

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News

Embryonic stem-cell research exempt from ban, NIH is told p185

Meredith Wadman

doi:10.1038/16507

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Insider trading alert over bioscience companies p185

Sally Lehrman

doi:10.1038/16511

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Space station faces research cuts to cover risk of Russian default p186

Tony Reichhardt

doi:10.1038/16513

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Biochemistry panel dropped from UK quality review p187

Natasha Loder

doi:10.1038/16516

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French scientists offered time to set up companies p187

Declan Butler

doi:10.1038/16518

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US genome researcher strikes it rich p187

doi:10.1038/16520

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India approves use of genetically modified crops, despite critics p188

K. S. Jayaraman

doi:10.1038/16523

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Physicist's dual role could help with Japanese merger p188

Asako Saegusa

doi:10.1038/16525

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Fossil dealer charged over Russian cache p189

Alison Abbott

doi:10.1038/16528

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Greens accept reprieve for neutron source p189

Quirin Schiermeier

doi:10.1038/16530

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Plan to limit Cambridge high-tech growth p190

Ehsan Masood

doi:10.1038/16533

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Quebec's tax incentives act as a magnet to research companies p190

David Spurgeon

doi:10.1038/16536

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Tough times set to continue for US biotech start-ups p191

Sally Lehrman

doi:10.1038/16539

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News in Brief p192

doi:10.1038/16541

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Briefings

The writing is on the web for science journals in print p195

The Internet revolution is injecting more competition into publishing and giving power back to scientists and learned societies. It presents new challenges to the guardians of the archives and could yet spell the end for many print titles.

This briefing has been written by Declan Butler

doi:10.1038/16544

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User consortia emerge as 'brokers' p196

doi:10.1038/16555

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Preserving papers for posterity p198

doi:10.1038/16557

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Roll over Gutenberg p200

doi:10.1038/16560

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Correspondence

Close the South-North knowledge gap p201

Vanderlei Canhos, Leslie Chan, Frances Giaquinto, Barbara Kirsop, Anthony ODonnell and Judy Ugonna

doi:10.1038/16562

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Luddites must not block progress in genetics p201

David Wood

doi:10.1038/16564

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Computers and the copyright conundrum p201

Dennis S. Karjala

doi:10.1038/16566

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Who pays what in drug development p202

James Love

doi:10.1038/16568

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Guard your knowledge ... and reap the rewards p202

David Grant

doi:10.1038/16570

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German university reforms misguided p202

Robin Ghosh

doi:10.1038/16572

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News and Views

Prospecting for Jurassic slabs p203

Mark A. Richards

doi:10.1038/16574

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Protein transport:  Molecular motors join forces p204

Manfred Schliwa

doi:10.1038/16577

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Reproductive biology:  Deep-sea clams feel the heat p205

Cindy Lee Van Dover

doi:10.1038/16580

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Quantum control:  Sculpting a wavepacket p207

Wolfgang P. Schleich

doi:10.1038/16583

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Stress responses:  Translational control perks up p208

Robert H. Silverman and Bryan R. G. Williams

doi:10.1038/16586

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100 and 50 years ago p209

doi:10.1038/16589

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Animal behaviour:  Monkey business in the aquarium p211

Rory Howlett

doi:10.1038/16591

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Condensed-matter science:  Ferroelectric ice p212

Steven T. Bramwell

doi:10.1038/16594

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Telomeres:  Capping off the ends p213

Carolyn Price

doi:10.1038/16598

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Bioinorganic chemistry:  Hydrogenase sophistication p214

Richard Cammack

doi:10.1038/16601

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Neurobiology:  A homeostatic switch p215

Richard Miles

doi:10.1038/16604

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Daedalus: Cogito in vitro p216

David Jones

doi:10.1038/16607

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Scientific Correspondence

Density-dependent warning coloration p217

Gregory A. Sword

doi:10.1038/16609

First paragraph | Full Text | PDF (78K)

Fas-mediated cell death promoted by opioids p218

Deling Yin, R. Allan Mufson, Ruoxiang Wang and Yufang Shi

doi:10.1038/16612

First paragraph | Full Text | PDF (81K)

Does global warming make Triton blush? p219

Bonnie J. Buratti, Michael D. Hicks and Ray L. Newburn, Jr

doi:10.1038/16615

First paragraph | Full Text | PDF (93K)

Shikimate pathway in apicomplexan parasites p219

Patrick J. Keeling, Jeffrey D. Palmer, Robert G. K. Donald, David S. Roos, Ross F. Waller and Geoffrey I. McFadden

doi:10.1038/16618

First paragraph | Full Text | PDF (93K)

Reply:  Shikimate pathway in apicomplexan parasites p220

Craig W. Roberts, John Finnerty, Jennifer J. Johnson, Fiona Roberts, Dennis E. Kyle, Tino Krell, John R Coggins, Graham H. Coombs, Wilbur K. Milhous, Saul Tzipori, David J. P. Ferguson, Debopam Chakrabarti and Rima McLeod

doi:10.1038/16621

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Book Reviews

Betwixt hagiography and debunking p221

W. F. Bynum

doi:10.1038/16623

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The face of the future p222

David Gems

doi:10.1038/16626

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Destruction and deliberation p223

Claudio Vita-Finzi

doi:10.1038/16629

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Antidote to angst p224

Gerhard Neuweiler

doi:10.1038/16632

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A 'playful physics' p224

doi:10.1038/16634

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Review

The large-scale smoothness of the Universe p225

Kelvin K. S. Wu, Ofer Lahav and Martin J. Rees

doi:10.1038/16637

Abstract | Full Text | PDF (887K)

Letters to Nature

The generation of martian floods by the melting of ground ice above dykes p231

Dan McKenzie and Francis Nimmo

doi:10.1038/16649

First paragraph | Full Text | PDF (321K)

Controlling the shape of a quantum wavefunction p233

T. C. Weinacht, J. Ahn and P. H. Bucksbaum

doi:10.1038/16654

First paragraph | Full Text | PDF (843K)

Nanometre-scale rolling and sliding of carbon nanotubes p236

M. R. Falvo, R. M. Taylor II, A. Helser, V. Chi, F. P. Brooks Jr, S. Washburn and R. Superfine

doi:10.1038/16662

First paragraph | Full Text | PDF (244K)

Identifying the forces responsible for self-organization of nanostructures at crystal surfaces p238

K. Pohl, M. C. Bartelt, J. de la Figuera, N. C. Bartelt, J. Hrbek and R. Q. Hwang

doi:10.1038/16667

First paragraph | Full Text | PDF (304K)

Coordinated proton tunnelling in a cyclic network of four hydrogen bonds in the solid state p241

Dermot F. Brougham, Roberto Caciuffo and Anthony J. Horsewill

doi:10.1038/16672

First paragraph | Full Text | PDF (274K)

Possible predictability in overflow from the Denmark Strait p243

Bob Dickson, Jens Meincke, Ian Vassie, Johann Jungclaus and Svein Østerhus

doi:10.1038/16680

First paragraph | Full Text | PDF (355K)

Mesozoic subducted slabs under Siberia p246

Rob Van der Voo, Wim Spakman and Harmen Bijwaard

doi:10.1038/16686

First paragraph | Full Text | PDF (389K)

Can aposematic signals evolve by gradual change? p249

Leena Lindström, Rauno V. Alatalo, Johanna Mappes, Marianna Riipi and Laura Vertainen

doi:10.1038/16692

First paragraph | Full Text | PDF (210K)

The K⁺/Cl^- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation p251

Claudio Rivera, Juha Voipio, John A. Payne, Eva Ruusuvuori, Hannele Lahtinen, Karri Lamsa, Ulla Pirvola, Mart Saarma and Kai Kaila

doi:10.1038/16697

First paragraph | Full Text | PDF (688K) | Supplementary information

Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL p255

Sylwester Chyb, Padinjat Raghu and Roger C. Hardie

doi:10.1038/16703

First paragraph | Full Text | PDF (1,356K)

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol p259

Thomas Hofmann, Alexander G. Obukhov, Michael Schaefer, Christian Harteneck, Thomas Gudermann and Günter Schultz

doi:10.1038/16711

First paragraph | Full Text | PDF (473K)

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28 p263

Andreas Hutloff, Anna M. Dittrich, Katja C. Beier, Barbara Eljaschewitsch, Regine Kraft, Ionnis Anagnostopoulos and Richard A. Kroczek

doi:10.1038/16717

First paragraph | Full Text | PDF (355K)

Direct interaction of microtubule- and actin-based transport motors p267

Jian-Dong Huang, Scott T. Brady, Bruce W. Richards, David Stenoien, James H. Resau, Neal G. Copeland and Nancy A. Jenkins

doi:10.1038/16722

First paragraph | Full Text | PDF (229K)

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase p271

Heather P. Harding, Yuhong Zhang and David Ron

doi:10.1038/16729

First paragraph | Full Text | PDF (385K)

New on the Market

Controlling a chain reaction p275

A selection of new products aimed at the DNA amplification market features PCR kits, and the paraphernalia needed to make use of them.
compiled by Brendan Horton from information provided by the manufacturers. c b B H f i p b t m

doi:10.1038/16734

Abstract | Full Text | PDF (119K)