Table of contents


Top

Opinion

Nuclear restraint is the difficult test p291

India's recent nuclear tests are a reminder that, despite recent progress in arms control, nuclear weapons remain a threat to humanity. Helping to prevent their use requires redoubled effort by the scientific community.

doi:10.1038/30544


Caveat investor p291

British Biotech's problems underline the need for scientific literacy in the stock market.

doi:10.1038/30546


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News

German technician's confession spurs check on suspect data p293

Alison Abbott

doi:10.1038/30548


Nature wins publishing award p293

doi:10.1038/30551


Entry standards to UK science courses fall p294

Ehsan Masood

doi:10.1038/30553


Japanese research 'must be more flexible' p294

Asako Saegusa

doi:10.1038/30556


Panel calls for fair deal for US postdocs p295

Colin Macilwain

doi:10.1038/30558


Computers hope to score at the football world cup for robots p295

Declan Butler

doi:10.1038/30560


Drosophila set for fast-track sequencing p296

David Dickson

doi:10.1038/30563


Venter backs call for more public funds p296

Meredith Wadman

doi:10.1038/30566


Universities win as South Africa reverses 1997 funding trend p297

Michael Cherry

doi:10.1038/30568


Bid to limit prices on drugs using 'public' discoveries p297

Meredith Wadman

doi:10.1038/30570


Indian scientists speak out against bomb p298

K. S. Jayaraman

doi:10.1038/30573


Despair over pay sparks Russian strike p298

Carl Levitin

doi:10.1038/30576


Chief to leave troubled British Biotech p299

Ehsan Masood

doi:10.1038/30578


Germans mix support and scepticism for genetic engineering p299

Quirin Schiermeier

doi:10.1038/30581


News in Brief p300

doi:10.1038/30583


Top

Correspondence

Bioprospecting for drugs p301

Gordon M. Cragg, David J. Newman and Stringner Sue Yang

doi:10.1038/30586


No convergence for references p301

Simonetta Sperti, Fiorenzo Stirpe and Maurizio Brigotti

doi:10.1038/30588


No laughing matter p301

Michael G. Vicker

doi:10.1038/30590


Unreliable errors p301

Bernard F. Erlanger

doi:10.1038/30592


Top

News and Views

Noble gases under pressure in the mantle p303

Minoru Ozima

doi:10.1038/30594


Notch signalling:  A short cut to the nucleus p304

Julian Lewis

doi:10.1038/30597


Colloids:  Ordering entropy p305

Henk N. W. Lekkerkerker and Alain Stroobants

doi:10.1038/30599


Evolutionary biology:  Land-loving crabs p305

Amanda Tromans

doi:10.1038/30601


100 and 50 years ago p307

doi:10.1038/30604


Molecular neurobiology:  The stress of Gulf War syndrome p308

Robert M. Sapolsky

doi:10.1038/30606


Materials science:  Silk and sequence p309

Paul Calvert

doi:10.1038/30610


Gene silencing:  Methylation meets acetylation p311

Timothy H. Bestor

doi:10.1038/30613


Aurorae:  Still in the dark p312

Joseph E. Borovsky

doi:10.1038/30616


Daedalus:  Current chemistry p313

David Jones

doi:10.1038/30620


Obituary:  Sir Frederick Charles Frank (1911-98) p314

John E. Enderby

doi:10.1038/30622


Top

Science and Image

Max's modelling p315

Models of molecular structures are not just useful aids in visualization and education for our understanding of the engineering of materials, but also reflect the styles of the dominant modes of design of their period.

Martin Kemp

doi:10.1038/30625


Top

Scientific Correspondence

X-ray flare sparks quake inside Sun p317

A. G. Kosovichev and V. V. Zharkova

doi:10.1038/30629


Low nitrate: phosphate ocean ratios corrected... p318

T. Tyrrell and C. S. Law

doi:10.1038/30632


...and database flagged p318

Margarita Conkright

doi:10.1038/30634


Global impact of the 1789-93 El Niño p318

Richard H. Grove

doi:10.1038/30636


Connexin 26 gene linked to a dominant deafness p319

Françoise Denoyelle, Genevieve Lina-Granade, Henri Plauchu, Roberto Bruzzone, Hassan Chaïb, Fabienne Lévi-Acobas, Dominique Weil and Christine Petit

doi:10.1038/30639


Transgene risk is low p320

Susan E. Scott and Mike J. Wilkinson

doi:10.1038/30642


Top

Book Reviews

Mad cows and secret agents p321

Adriano Aguzzi reviews Fatal Protein: The Story of CJD, BSE and Other Prion Diseases by Rosalind M. Ridley and Harry F. Baker

doi:10.1038/30645


Computer evolution p322

Philip W. Anderson reviews Darwin Among the Machines by George Dyson

doi:10.1038/30648


Body of evidence p323

Roy Porter reviews Hermaphrodites and the Medical Invention of Sex by Alice Domurat Dreger

doi:10.1038/30651


Movers and shakers p324

Graham A. Dunn reviews Motion Analysis of Living Cells edited by David R. Soll and Deborah Wessels

doi:10.1038/30655


Breaking the law p324

Peter T. Landsberg reviews Maxwell's Demon: Why Warmth Disperses and Time Passes by Hans Christian von Baeyer

doi:10.1038/30657


New Journals p324

doi:10.1038/30659


Top

Review

Global warming and the stability of the West Antarctic Ice Sheet p325

Michael Oppenheimer

doi:10.1038/30661


Top

Article

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor p333

Linda M. McLatchie, Neil J. Fraser, Martin J. Main, Alan Wise, Jason Brown, Nicola Thompson, Roberto Solari, Melanie G. Lee and Steven M. Foord

doi:10.1038/30666


Top

Letters to Nature

Reflected infrared spectrum of a massive protostar in Orion p340

Jun-Ichi Morino, Takuya Yamashita, Tetsuo Hasegawa and Takenori Nakano

doi:10.1038/30678


Relation to solar activity of intense aurorae in sunlight and darkness p342

Patrick T. Newell, Ching-I. Meng and Simon Wing

doi:10.1038/30682

See also: News and Views by Borovsky


Implementation of a quantum search algorithm on a quantum computer p344

Jonathan A. Jones, Michele Mosca and Rasmus H. Hansen

doi:10.1038/30687


Carbon nanotubule membranes for electrochemical energy storage and production p346

Guangli Che, Brinda B. Lakshmi, Ellen R. Fisher and Charles R. Martin

doi:10.1038/30694


Entropically driven microphase transitions in mixtures of colloidal rods and spheres p349

Marie Adams, Zvonimir Dogic, Sarah L. Keller and Seth Fraden

doi:10.1038/30700

See also: News and Views by Lekkerkerker & Stroobants


Low argon solubility in silicate melts at high pressure p352

Eva Chamorro-Pérez, Philippe Gillet, Albert Jambon, James Badro and Paul McMillan

doi:10.1038/30706

See also: News and Views by Ozima


Rare-gas solids in the Earth's deep interior p355

Andrew P. Jephcoat

doi:10.1038/30712

See also: News and Views by Ozima


Optical and radiocarbon dating at Jinmium rock shelter in northern Australia p358

Richard Roberts, Michael Bird, Jon Olley, Rex Galbraith, Ewan Lawson, Geoff Laslett, Hiroyuki Yoshida, Rhys Jones, Richard Fullagar, Geraldine Jacobsen and Quan Hua

doi:10.1038/30718


Rapid evolution to terrestrial life in Jamaican crabs p363

Christoph D. Schubart, Rudolf Diesel and S. Blair Hedges

doi:10.1038/30724

See also: News and Views by Tromans


The biosynthetic pathway of vitamin C in higher plants p365

Glen L. Wheeler, Mark A. Jones and Nicholas Smirnoff

doi:10.1038/30728


Visual input evokes transient and strong shunting inhibition in visual cortical neurons p369

Lyle J. Borg-Graham, Cyril Monier and Yves Frégnac

doi:10.1038/30735


Acute stress facilitates long-lasting changes in cholinergic gene expression p373

Daniela Kaufer, Alon Friedman, Shlomo Seidman and Hermona Soreq

doi:10.1038/30741

See also: News and Views by Sapolsky


Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A p377

Saumya Das, Yasnory F. Sasaki, Thomas Rothe, Louis S. Premkumar, Mari Takasu, James E. Crandall, Pieter Dikkes, David A. Conner, Posina V. Rayudu, Wing Cheung, H.-S. Vincent Chen, Stuart A. Lipton and Nobuki Nakanishi

doi:10.1038/30748


Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain p382

Eric H. Schroeter, Jeffrey A. Kisslinger and Raphael Kopan

doi:10.1038/30756

See also: News and Views by Lewis


Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex p386

Xinsheng Nan, Huck-Hui Ng, Colin A. Johnson, Carol D. Laherty, Bryan M. Turner, Robert N. Eisenman and Adrian Bird

doi:10.1038/30764

See also: News and Views by Bestor


Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo p389

Dong-ki Lee and John T. Lis

doi:10.1038/30770


Atomic structure of progesterone complexed with its receptor p392

Shawn P. Williams and Paul B. Sigler

doi:10.1038/30775


correction: Low nitrate: phosphate ratios in the global ocean p396

T. Tyrrell and C. S. Law

doi:10.1038/30780


correction: A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD p396

Masato Enari, Hideki Sakahira, Hideki Yokoyama, Katsuya Okawa, Akihiro Iwamatsu and Shigekazu Nagata

doi:10.1038/30782


correction: Phase-mapping of periodically domain-inverted LiNbO3 with coherent X-rays p396

Z. W. Hu, P. A. Thomas, A. Snigirev, I. Snigireva, A. Souvorov, P. G. R. Smith, G. W. Ross and S. Teat

doi:10.1038/30784


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