Opinion

Time for determination and hope in Russia p533

A new mood of optimism can be found in many parts of Russia's scientific community that has been absent for much of the past five years. But it must not be allowed to turn into complacency; many hurdles remain.

doi:10.1038/42304

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News

New French government aims to boost research job prospects p535

Declan Butler

doi:10.1038/42306

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Russian academy elects younger blood p535

Carl Levitin

doi:10.1038/42308

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Germany rejects genome data 'isolation' p536

Alison Abbott

doi:10.1038/42311

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European ethics advisers back cloning ban p536

Declan Butler

doi:10.1038/42313

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EU eliminates citation gap with America p537

doi:10.1038/42315

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Europe seeks to head off oil-exporters' veto on climate treaty p537

Ehsan Masood

doi:10.1038/42319

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Microsoft 'in talks' to set up research base in Cambridge p538

Ehsan Masood

doi:10.1038/42321

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Italian universities move to peer review for grants p538

Alison Abbott

doi:10.1038/42323

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Politics fuels French synchrotron row p539

Declan Butler

doi:10.1038/42326

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France and Britain drop idea of joint machine p539

Declan Butler

doi:10.1038/42329

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Geologist loses 'creationism' challenge p540

Peter Pockley

doi:10.1038/42331

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US threat to end science agreement with India over patent law p540

K. S. Jayaraman

doi:10.1038/42335

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News Analysis

Weapons labs turn to computer simulation p541

US nuclear weapons laboratories are moving to a regime based on linking experiment and computer simulation. But can they win over their critics?

Colin Macilwain

doi:10.1038/42337

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News in Brief p542

doi:10.1038/42340

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Correspondence

Science as a cultural construct p543

Andrew Pickering

doi:10.1038/42342

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Patents and royalties p546

Robert B. Helling

doi:10.1038/42345

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News and Views

Words and rules in the human brain p547

Steven Pinker

doi:10.1038/42347

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Quantum mechanics:  Quantum procrastination p548

P. T. Greenland

doi:10.1038/42350

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Molecular systematics:  The platypus put in its place p549

David Penny & Masami Hasegawa

doi:10.1038/42352

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Evolutionary biology:  Is speciation no accident? p551

Roger K. Butlin & Tom Tregenza

doi:10.1038/42355

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Archaeology:  Husbandry at the oldest henge p553

Elizabeth Aveling

doi:10.1038/42359

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Circadian rhythms:  Time to get excited by GABA p554

Christopher S. Colwell

doi:10.1038/42362

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Biosensors:  Switching channels makes sense p555

Anthony P. F. Turner

doi:10.1038/42365

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100 and 50 years ago p555

doi:10.1038/42368

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Microbial genetics:  Hypermutation under stress p557

Bryn A. Bridges

doi:10.1038/42370

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Electromagnetism:  The secret life of the dipole p558

Jeeva S. Anandan

doi:10.1038/42372

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Daedalus:  Flower power p559

David Jones

doi:10.1038/42376

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Obituary:  Norman Pirie (1907-97) p560

Leslie Fowden & Stan Pierpoint

doi:10.1038/42378

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Scientific Correspondence

Why drinking green tea could prevent cancer p561

Jerzy Jankun, Steven H. Selman, Rafal Swiercz & Ewa Skrzypczak-Jankun

doi:10.1038/42381

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Domatia mediate plantarthropod mutualism p562

Anurag A. Agrawal & Richard Karban

doi:10.1038/42384

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Salt enhances flavour by suppressing bitterness p563

P. A. S. Breslin & G. K. Beauchamp

doi:10.1038/42388

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Structures of mollusc shell framework proteins p563

Shu Sudo, Takahiko Fujikawa, Takeshi Nagakura, Takeshi Ohkubo, Kesami Sakaguchi, Minoru Tanaka, Kunio Nakashima & Takao Takahashi

doi:10.1038/42391

First paragraph | Full Text | PDF (150K)

Book Reviews

Speculation on population p565

Joel E. Cohen

doi:10.1038/42395

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Bleak houses p565

doi:10.1038/42397

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Nostalgia for the USSR p566

Zhores A. Medvedev

doi:10.1038/42400

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Squabbles in space p567

Roy Gibson

doi:10.1038/42403

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Creatures of mystery p568

J. L . Cloudsley-Thompson

doi:10.1038/42405

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Progress

Functional rafts in cell membranes p569

Kai Simons & Elina Ikonen

doi:10.1038/42408

Abstract | Full Text | PDF (326K)

Letters to Nature

A new dynamical class of object in the outer Solar System p573

Jane Luu, Brian G. Marsden, David Jewitt, Chadwick A. Trujillo, Carl W. Hergenrother, Jun Chen & Warren B. Offutt

doi:10.1038/42413

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Experimental evidence for non-exponential decay in quantum tunnelling p575

Steven R. Wilkinson, Cyrus F. Bharucha, Martin C. Fischer, Kirk W. Madison, Patrick R. Morrow, Qian Niu, Bala Sundaram & Mark G. Raizen

doi:10.1038/42418

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Chiral discrimination using piezoelectric and optical gas sensors p577

K. Bodenhöfer, A. Hierlemann, J. Seemann, G. Gauglitz, B. Koppenhoefer & W. Gpel

doi:10.1038/42426

First paragraph | Full Text | PDF (284K)

A biosensor that uses ion-channel switches p580

B. A. Cornell, V. L. B. Braach-Maksvytis, L. G. King, P. D. J. Osman, B. Raguse, L. Wieczorek & R. J. Pace

doi:10.1038/42432

First paragraph | Full Text | PDF (377K) | Supplementary information

Synthesis and X-ray structure of dumb-bell-shaped C₁₂₀ p583

Guan-Wu Wang, Koichi Komatsu, Yasujiro Murata & Motoo Shiro

doi:10.1038/42439

First paragraph | Full Text | PDF (285K) | Supplementary information

The Lu–Hf dating of garnets and the ages of the Alpine high-pressure metamorphism p586

S. Duch&;ecirc;ne, J. Blichert-Toft, B. Luais, P. Télouk, J.-M. Lardeaux & F. Albarède

doi:10.1038/42446

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A sexually selected character displacement in flycatchers reinforces premating isolation p589

Glenn-Peter Stre, Truls Moum, Stanislav Bure, Miroslav Král, Martin Adamjan & Juan Moreno

doi:10.1038/42451

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Dissociating types of mental computation p592

William D. Marslen-Wilson & Lorraine K. Tyler

doi:10.1038/42456

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Distortions of visuotopic map match orientation singularities in primary visual cortex p594

Aniruddha Das & Charles D. Gilbert

doi:10.1038/42461

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GABA in the mammalian suprachiasmatic nucleus and its role in diurnal rhythmicity p598

Shlomo Wagner, Mona Castel, Harold Gainer & Yosef Yarom

doi:10.1038/42468

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The Rx homeobox gene is essential for vertebrate eye development p603

P. H. Mathers, A. Grinberg, K. A. Mahon & M. Jamrich

doi:10.1038/42475

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The putative chaperone calmegin is required for sperm fertility p607

Masahito Ikawa, Ikuo Wada, Katsuya Kominami, Daisuke Watanabe, Kiyotaka Toshimori, Yoshitake Nishimune & Masaru Okabe

doi:10.1038/42484

First paragraph | Full Text | PDF (678K)

Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation p611

Yang Pan, Clare Lloyd, Hong Zhou, Sylvia Dolich, Jim Deeds, Jose-Angel Gonzalo, Jim Vath, Mike Gosselin, Jingya Ma, Barry Dussault, Elizabeth Woolf, Geoff Alperin, Janice Culpepper, Jose Carlos Gutierrez-Ramos & David Gearing

doi:10.1038/42491

First paragraph | Full Text | PDF (495K)

Ligand-specific oligomerization of T-cell receptor molecules p617

Ziv Reich, J. Jay Boniface, Daniel S. Lyons, Nina Borochov, Ellen J. Wachtel & Mark M. Davis

doi:10.1038/42500

First paragraph | Full Text | PDF (292K)

A G-protein-coupled receptor for leukotriene B₄ that mediates chemotaxis p620

Takehiko Yokomizo, Takashi Izumi, Kyungho Chang, Yoh Takuwa & Takao Shimizu

doi:10.1038/42506

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The three-dimensional structure of aquaporin-1 p624

Thomas Walz, Teruhisa Hirai, Kazuyoshi Murata, J. Bernard Heymann, Kaoru Mitsuoka, Yoshinori Fujiyoshi, Barbara L. Smith, Peter Agre & Andreas Engel

doi:10.1038/42512

First paragraph | Full Text | PDF (2,410K)

Three-dimensional organization of a human water channel p627

Anchi Cheng, A. N. van Hoek, M. Yeager, A. S. Verkman & A. K. Mitra

doi:10.1038/42517

First paragraph | Full Text | PDF (1,240K)

Crystal structure of the complex between human CD8 and HLA-A2 p630

George F. Gao, José Tormo, Ulrich C. Gerth, Jessica R. Wyer, Andrew J. McMichael, David I. Stuart, John I. Bell, E. Yvonne Jones & Bent K. Jakobsen

doi:10.1038/42523

First paragraph | Full Text | PDF (553K)

Correction:  CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes p634

K. Christopher Garcia, Christopher A. Scott, Anders Brunmark, Francis R. Carbone, Per A. Peterson, Ian A. Wilson & Luc Teyton

doi:10.1038/42529

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New on the Market

Achema assembly p635

Converging on Frankfurt, Germany, scientists at Achema may find an assortment of analytical and data handling tools, such as a second-generation excitation source, a Java toolkit for data handling and data acquisition software.

compiled by Brendan Horton from information provided by the manufacturers.

doi:10.1038/42532

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