| | Opinion |  |
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| | The dangers of the university business 579
Universities are not businesses; attempts to run them as if they were risk trouble, as with two minor embarrassments at new British universities.
doi:10.1038/372579a0
PDF (235K)
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| | Apaches against stars 580
There is no merit in the campaign of the Apache Survival Coalition against the Mount Graham telescope.
doi:10.1038/372580a0
PDF (131K)
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| | News and Views |  |
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| | LHC is set for approval by CERN-if France agrees to play ball 581
David Dickson
doi:10.1038/372581a0
PDF (268K)
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| | Bid to raise interest in research 581
doi:10.1038/372581b0
PDF (137K)
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| | Figures reveal Europe still falling behind US research 582
Declan Butler
doi:10.1038/372582a0
PDF (131K)
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| | Nuclear industry seek US/Europe agreement on export controls 582
Maggie Verrall
doi:10.1038/372582b0
PDF (131K)
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| | EPA reveals plans to double external grants 583
Tony Reichhardt
doi:10.1038/372583a0
PDF (141K)
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| | DNA, sex and the single macaw 583
Maggie Verrall
doi:10.1038/372583b0
PDF (141K)
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| | News | |
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| | Coalition pursues ban on animals in teaching 584
Alison Abbott
doi:10.1038/372584a0
PDF (145K)
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| | Moscow meeting raises research fund hopes 584
Tony Reichhardt
doi:10.1038/372584b0
PDF (145K)
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| | Livermore head promises openness 584
Sally Lehrmann
doi:10.1038/372584c0
PDF (145K)
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| | Australia's CSIRO takes the flak from Senate committee 585
Mark Lawson
doi:10.1038/372585a0
PDF (140K)
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| | Biodiversity treaty nations to study biosafety protocol 585
Daniel Putterman
doi:10.1038/372585b0
PDF (140K)
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| | Row over industry link-up splits staff of Spanish lab 586
Luis-Angel Fernandez Hermana
doi:10.1038/372586a0
PDF (160K)
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| | CNRS agrees to pay up over destruction of computer files 586
Declan Butler
doi:10.1038/372586b0
PDF (160K)
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| | UN AIDS chief will 'mobilize' commitment... 587
Declan Butler
doi:10.1038/372587a0
PDF (135K)
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| | MPG outlines new plans for eastern Germany 587
Alison Abbott
doi:10.1038/372587b0
PDF (135K)
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| | ... as tighter research links urged 587
Sally Lehrman
doi:10.1038/372587c0
PDF (135K)
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| | Correspondence | |
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| | Remarkable and novel increase 588
John MacDermot
doi:10.1038/372588a0
PDF (126K)
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| | Alas, poor title 588
Anne Moon & Nathan Machin
doi:10.1038/372588b0
PDF (126K)
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| | Bright spark? 588
Thomas C. Nelson
doi:10.1038/372588c0
PDF (126K)
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| | Randomization 588
Richard Peto & Rory Collins
doi:10.1038/372588d0
References | PDF (126K)
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| | Training for Africans in Africa 589
Noël Cameron, Lee R. Berger & Jeffrey K. McKee
doi:10.1038/372589a0
PDF (129K)
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| | Population control not the answer 589
Thomas A. Bicsak
doi:10.1038/372589b0
PDF (129K)
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| | Telescope site at Mount Graham 589
Ola Cassadore Davis
doi:10.1038/372589c0
PDF (129K)
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| | Commentary |  |
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| | Science for art's sake 590
Hollywood's absent-minded professor, always a cliché, is now more unrealistic than ever before. Just how can biological research move forward in the modern era?
Sukumar Vijayaraghavan
doi:10.1038/372590a0
PDF (126K)
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| | SCIENCE IN CENTRAL EUROPE | |
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| | What next for science in Central Europe? 591
This survey of science in Central Europe, the first of two, raises questions about the degree to which the planners of the new regimes should be constrained by the habits of the old. More radicalism would be welcome.
doi:10.1038/372591a0
PDF (386K)
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| | Polish science stands at the crossroads 593
David Dickson
doi:10.1038/372593a0
PDF (1,042K)
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| | Historical figure hits the high notes 593
doi:10.1038/372593b0
PDF (361K)
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| | A crusading reformer with a mission 594
doi:10.1038/372594a0
PDF (286K)
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| | Academy rides the winds of change 595
doi:10.1038/372595a0
PDF (399K)
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| | Universities struggle to grow 596
doi:10.1038/372596a0
PDF (304K)
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| | Dream meets reality of Euro-funding 596
doi:10.1038/372596b0
PDF (304K)
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| | Exploiting a medical tradition 597
doi:10.1038/372597a0
PDF (140K)
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| | Peer review: a call for help 597
doi:10.1038/372597b0
PDF (140K)
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| | Separate Slovakia's struggles 598
Alison Abbott
doi:10.1038/372598a0
PDF (144K)
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| | Shrinking asset for funding 598
doi:10.1038/372598b0
PDF (289K)
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| | New plant in ancient soil 599
doi:10.1038/372599a0
PDF (281K)
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| | Looking separately to the West 600
doi:10.1038/372600a0
PDF (136K)
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| | Czekh's streamlined academy 601
Alison Abbott
doi:10.1038/372601a0
PDF (234K)
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| | What's in a name? 601
doi:10.1038/372601b0
PDF (234K)
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| | Czech universities go slow 602
doi:10.1038/372602a0
PDF (541K)
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| | Who should give PhDs? 602
doi:10.1038/372602b0
PDF (403K)
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| | Institute living on its wits 603
doi:10.1038/372603a0
PDF (455K)
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| | Clinical efficiency 604
doi:10.1038/372604a0
PDF (318K)
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| | Why be a scientist? 604
doi:10.1038/372604b0
PDF (318K)
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| | Romania after the Ceau escus 605
Alison Abbott
doi:10.1038/372605a0
PDF (288K)
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| | Uncontrolled university boom 606
doi:10.1038/372606a0
PDF (145K)
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| | Bootstrapping a new institute 607
doi:10.1038/372607a0
PDF (312K)
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| | Taxing times for research funds 607
doi:10.1038/372607b0
PDF (312K)
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| | Old academies of sciences in transition 608
The academies of sciences in the countries of the former Soviet Union, Eastern and Central Europe no longer have a decorative role in national affairs, but are remarkably confident that the worst is now over.
doi:10.1038/372608a0
PDF (468K)
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| | Bulgaria — cutting to the bone 609
Carl Levitin
doi:10.1038/372609a0
PDF (294K)
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| | How to survive in business 609
doi:10.1038/372609b0
PDF (294K)
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| | Ecology benefits from decay 610
doi:10.1038/372610a0
PDF (229K)
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| | World Cup — an excuse to celebrate 610
doi:10.1038/372610b0
PDF (229K)
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| | A phoenix flies 610
doi:10.1038/372610c0
PDF (229K)
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| | Attrition in change 610
doi:10.1038/372610d0
PDF (229K)
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| | News and Views | |
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| | The future history of the Solar System 611
The belief that the Sun will eventually mechanically engulf the orbit of the Earth may be misplaced, but even the coming billion years could bring discomfort to the Earth's inhabitants.
John Maddox
doi:10.1038/372611a0
PDF (137K)
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| | Ice cores north and south 612
Jean Jouzel
doi:10.1038/372612a0
References | PDF (258K)
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| | Faces, fear and the amygdala 613
John Allman & Leslie Brothers
doi:10.1038/372613a0
References | PDF (130K)
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| | Knowing when to stop 614
Mick F. Tuite & Ian Stansfield
doi:10.1038/372614a0
References | PDF (308K)
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| | Chewing the fat 615
Peter Parham
doi:10.1038/372615a0
References | PDF (261K)
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| | February's bizarre event 616
Peter J. T. Leonard
doi:10.1038/372616a0
References | PDF (262K)
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| | Meteorite made with a fizz 616
Karl Ziemelis
doi:10.1038/372616b0
PDF (129K)
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| | What promise for dendrimers? 617
DonaId A. Tomalia & Petar R. Dvornic
doi:10.1038/372617a0
References | PDF (304K)
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| | Endogenous cannabinoids 619
Leslie Iversen
doi:10.1038/372619a0
References | PDF (156K)
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| | Silence speaks in spectrin 620
Walter Gratzer
doi:10.1038/372620a0
References | PDF (311K)
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| | Fast flickers in the tropics 621
Rainer Zahn
doi:10.1038/372621a0
References | PDF (304K)
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| | Scan the Heavens 622
David Jones
doi:10.1038/372622a0
PDF (173K)
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| | Scientific Correspondence | |
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| | Avian endemism and forest loss 623
Andrew Balmford & Adrian Long
doi:10.1038/372623a0
References | PDF (236K)
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| | Unexpected activity of saporins 624
Luigi Barbieri, Paola Gorini, Paola Valbonesi, Paola Castiglioni & Fiorenzo Stirpe
doi:10.1038/372624a0
References | PDF (133K)
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| | Climate, CO2 and plant abundance 625
T. W. Boutton, S. R. Archer & L. C. Nordt
doi:10.1038/372625a0
References | PDF (291K)
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| | Climate, CO2 and plant abundance 626
H. Curtis Monger & David R. Cole
doi:10.1038/372626a0
References | PDF (163K)
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| | CO2 effects at high temperature 626
John H. Lawton
doi:10.1038/372626b0
References | PDF (164K)
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| | Replication step 626
Charles Weissman
doi:10.1038/372626c0
PDF (164K)
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| | Book Reviews | |
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| | Dilemmas and missions 627
A. G. Keller reviews The Fontana History of Technology
By
Donald Cardwell, R. A. Buchanan & Richard L. Hills
doi:10.1038/372627a0
PDF (254K)
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| | Making waves 628
Willem Hackman reviews The Creation of Scientific Effects: Heinrich Hertz and Electric Waves.
By
Jed Z. Buchwald
doi:10.1038/372628a0
PDF (294K)
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| | The problems of little and large 629
H. C. Bennet-Clark reviews Diatoms to Dinosaurs: The Size and Scale of Living Things
By
Christopher McGowan
doi:10.1038/372629a0
PDF (399K)
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| | Ins and outs 630
P. R. Stanfield reviews Handbook of Membrane Channels
Edited by
Camillo Peracchia, John H. Byrne & Stanley G. Schultz
doi:10.1038/372630a0
PDF (233K)
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| | Progress | |
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| | Protein superfamilles and domain superfolds 631
Christine A. Orengo, David T. Jones & Janet M. Thornton
doi:10.1038/372631a0
Abstract & References | PDF (565K)
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| | Articles |  |
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| | An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita 635
Elena Zanaria, Françoise Muscatelli, Barbara Bardoni, Tim M. Strom, Silvana Guioli, Weiwen Guo, Enzo Lalli, Claudio Moser, Ann P. Walker, Edward R. B. McCabe, Thomas Meitinger, Anthony P. Monaco, Paolo Sassone-Corsi & Giovanna Camerino
doi:10.1038/372635a0
Abstract & References | PDF (1,143K)
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| |
In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence 642
Yen Choo, Isidro Sánchez-García & Aaron Klug
doi:10.1038/372642a0
Abstract & References | PDF (421K)
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| | Conformation of GroEL-bound  -lactalbumin probed by mass spectrometry 646
Carol V. Robinson, Michael Gro , Stephen J. Eyles, Jonathan J. Ewbank, Mark Mayhew, F. Ulrich Hartl, Christopher M. Dobson & Sheena E. Radford
doi:10.1038/372646a0
Abstract & References | PDF (805K)
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| | Letters | |
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| | Detection of a  -ray burst of very long duration and very high energy 652
K. Hurley, B. L. Dingus, R. Mukherjee, P. Sreekumar, C. Kouveliotou, C. Meegan, G. J. Fishman, D. Band, L. Ford, D. Bertsch, T. Cline, C. Fichtel, R. Hartman, S. Hunter, D. J. Thompson, G. Kanbach, H. Mayer-Hasselwander, C. von Montigny, M. Sommer, Y. Lin, P. Nolan, P. Michelson, D. Kniffen, J. Mattox, E. Schneid, M. Boer & M. Niel
doi:10.1038/372652a0
First paragraph & References | PDF (293K)
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| | Record of fluid–rock interactions on Mars from the meteorite ALH84001 655
C. S. Romanek, M. M. Grady, I. P. Wright, D. W. Mittlefehldt, R. A. Socki, C. T. Pillinger & E. K. Gibson Jr
doi:10.1038/372655a0
First paragraph & References | PDF (383K)
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| | Surface spectroscopy with high spatial resolution using metastable atoms 657
Y. Harada, S. Yamamoto, M. Aoki, S. Masuda, T. Ichinokawa, M. Kato & Y. Sakai
doi:10.1038/372657a0
First paragraph & References | PDF (341K)
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| | Homogeneous catalysts based on silane dendrimers functionalized with arylnickel(II) complexes 659
Joan W. J. Knapen, Alexander W. van der Made, Janine C. de Wilde, Piet W. N. M. van Leeuwen, Peter Wijkens, David M. Grove & Gerard van Koten
doi:10.1038/372659a0
First paragraph & References | PDF (722K)
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| | Climate correlations between Greenland and Antarctica during the past 100,000 years 663
Michael Bender, Todd Sowers, Mary-Lynn Dickson, Joseph Orchardo, Pieter Grootes, Paul A. Mayewski & Debra A. Meese
doi:10.1038/372663a0
First paragraph & References | PDF (506K)
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| | The role of deep roots in the hydrological and carbon cycles of Amazonian forests and pastures 666
Daniel C. Nepstad, Claudio R. de Carvalho, Eric A. Davidson, Peter H. Jipp, Paul A. Lefebvre, Gustavo H. Negreiros, Elson D. da Silva, Thomas A. Stone, Susan E. Trumbore & Simone Vieira
doi:10.1038/372666a0
First paragraph & References | PDF (501K)
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|
| | Impaired recognition of emotion in facial expressions following bilateral damage to the human amygdala 669
R. Adolphs, D. Tranel, H. Damasio & A. Damasio
doi:10.1038/372669a0
First paragraph & References | PDF (525K)
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| | Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism 672
Françoise Muscatelli, Tim M. Strom, Ann P. Walker, Elena Zanaria, Dominique Récan, Alfons Meindl, Barbara Bardoni, Silvana Guioli, Günther Zehetner, Wolfgang Rabl, Hans Peter Schwarz, Jean-Claude Kaplan, Giovanna Camerino, Thomas Meitinger & Anthony P. Monaco
doi:10.1038/372672a0
First paragraph & References | PDF (467K)
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|
| | Role of the LIM class homeodomain protein Xlim-1 in neural and muscle induction by the Spemann organizer in Xenopus
677
Masanorl Taira, Hlroki Otani, Jean-Pierre Saint-Jeannet & Igor B. Dawid
doi:10.1038/372677a0
First paragraph & References | PDF (447K)
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| | Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4
679
Kevin Stark, Seppo Vainio, Galya Vassileva & Andrew P. McMahon
doi:10.1038/372679a0
First paragraph & References | PDF (731K)
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|
| | The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest 684
Anthony Graham, Philippa Francis-West, Paul Brickell & Andrew Lumsden
doi:10.1038/372684a0
First paragraph & References | PDF (520K)
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| | Formation and inactivation of endogenous cannabinoid anandamide in central neurons 686
Vincenzo Di Marzo, Angelo Fontana, Hugues Cadas, Sergio Schinelli, Guido Cimino, Jean-Charles Schwartz & Danlele Piomelli
doi:10.1038/372686a0
First paragraph & References | PDF (648K)
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|
| | Recognition of a lipid antigen by GDI-restricted  + T cells 691
Evan M. Beckman, Steven A. Porcelli, Craig T. Morita, Samuel M. Behar, Stephen T. Furlong & Michael B. Brenner
doi:10.1038/372691a0
First paragraph & References | PDF (413K)
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|
| | A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with antiviral activity in vivo
695
Michel Liuzzi, Robert Déziel, Nell Moss, Pierre Beaulieu, Anne-Marie Bonneau, Christiane Bousquet, James G. Chafouleas, Michel Garneau, Jorge Jaramillo, Richard L. Krogsrud, Lisette Lagacé, Robert S. McCollum, Sopone Nawoot & Yvan Guindon
doi:10.1038/372695a0
First paragraph & References | PDF (425K)
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| | Ypt1p implicated in v-SNARE activation 698
Jian P. Lian, Shelly Stone, Yu Jiang, Patrick Lyons & Susan Ferro-Novick
doi:10.1038/372698a0
First paragraph & References | PDF (504K)
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| | A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor 701
Lyudmila Frolova, Xavier Le Goff, Hanne H. Rasmussen, Sergey Cheperegin, Gabriele Drugeon, Michel Kress, Inga Arman, Anne-Lise Haenni, Jullo E. Celis, Michel Phllippe, Just Justesen & Lev Kisselev
doi:10.1038/372701a0
First paragraph & References | PDF (358K)
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| | Structure of the human ADP-ribosylation factor 1 complexed with GDP 704
Juan Carlos Amor, David H. Harrison, Richard A. Kahn & Dagmar Ringe
doi:10.1038/372704a0
First paragraph & References | PDF (726K)
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| | Corrections | |
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| | Self-assembling organic nanotubes based on a cyclic peptide architecture 709
M. Juan R. Reza GhadiriGranja, Ronald A. Milligan, Duncan E. McRee & Nina Khazanovich
doi:10.1038/372709a0
References | PDF (71K)
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| | A deep earthquake aftershock sequence and implications for the rupture mechanism of deep earthquakes 709
Douglas A. Wiens, Jeffrey J. McGuire, Patrick J. Shore, Michael G. Bevis, Kitione Draunidalo, Gajendra Prasad & Saimone P. Helu
doi:10.1038/372709b0
PDF (71K)
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| | A TCP1-related molecular chaperone from plants refolds phytochrome to its photoreversible form 709
Eckart Mummert, Rudolf Grimm, Volker Speth, Christoph Eckerskorn, Emile Schiltz, Anthony A. Gatenby & Eberhard Schäfer
doi:10.1038/372709c0
References | PDF (71K)
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| | Errata | |
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| | A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells 710
C. Stephen Downes, Duncan J. Clarke, Ann M. Mullinger, Juan F. Giménez-Abián, Andrew M. Creighton & Robert T. Johnson
doi:10.1038/372710a0
PDF (141K)
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| | Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene 710
Eiichi Araki, Myra A. Lipes, Mary-Elizabeth Patti, Jens Claus Brüning, Burritt Haag III, Randall S. Johnson & C. Ronald Kahn
doi:10.1038/372710b0
PDF (141K)
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