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A light-scattering method implemented by using fibre-optic technology that can be directly incorporated into standard vascular-access devices allows for real-time monitoring of blood coagulability in the operating room.
A rapid, inexpensive and ultrasensitive assay that uses antibody-conjugated nanoparticle probes on the surface of a sensor chip quantifies tumour-derived extracellular vesicles to detect pancreatic cancer from 1 μl of blood plasma.
A man/machine interface based on the activity of spinal motor neurons reinnervating the muscles of a missing limb in amputees enables the generation of neural signals for potential prosthetic control.
By taking advantage of stimulated Raman spectroscopy and fibre-laser technology, virtual histology images can be obtained in real time in the operating room, with diagnostic quality comparable with that achieved via conventional histopathology.
A biocompatible, energy-harvesting electrochemical cell delivers power to a wireless sensor for an average of 6.1 days of temperature measurements in the gastrointestinal tract of pigs.
An artificial intelligence agent integrated with a cloud-based platform for multihospital collaboration performs equally as well as ophthalmologists in the diagnosis of congenital cataracts in a series of online tests and a multihospital clinical trial.
By targeting the surgical bed and circulating tumour cells, platelets conjugated with an antibody against an immune checkpoint protein prevent tumour recurrence and metastasis following resection of the primary tumour.
A hand-spun centrifuge made of paper and string can separate plasma from whole blood in less than two minutes, and be used to diagnose malaria and other infectious diseases in areas without laboratory resources or electricity.
A chemically defined protocol requiring no animal-derived components allows for the easier derivation and enduring expansion of epicardial cells from human pluripotent stem cells.
Conjugation of a diabetes drug with a brush polymer reduces the reactivity of the drug conjugate towards pre-existing polymer antibodies in human plasma and improves the drug's performance in diabetic mice.
A hand-powered centrifuge made of two paper discs, string and wooden handles is shown to achieve rotational speeds of 125,000 r.p.m., separate pure plasma from whole blood in less than 1.5 minutes and isolate malaria parasites in 15 minutes.