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December 2000, Volume 14, Number 12

Table of Contents

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Editorial
The dilemma of apoptosis in myelodysplasia and leukemia: a new promise of therapeutic intervention? FREE
M V Blagosklonny
Abstract  |  Full text  |  PDF 2017
Spotlight on Apoptosis
Kinases: positive and negative regulators of apoptosis FREE
R A Franklin & J A McCubrey
Abstract  |  Full text  |  PDF 2019
Review and Meeting Report
Dissecting the pathways to death FREE
P T Daniel
Abstract  |  Full text  |  PDF 2035
Original Manuscripts
Expression and activity of caspases 1 and 3 in myelodysplastic syndromes FREE
D Boudard, O Sordet, C Vasselon, V Revol, M-F Berthéas, D Freyssenet, A Viallet, S Piselli, D Guyotat & L Campos
Abstract  |  Full text  |  PDF 2045
Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies FREE
A Mengarelli, A P Iori, C Guglielmi, M P Perrone, M Gozzer, C Girmenia, G Cimino, A M Testi, R Ricci, L De Felice, G Girelli, F Mandelli & W Arcese
Abstract  |  Full text  |  PDF 2052
Prognosis of patients with a second relapse of acute myeloid leukemia FREE
B Stoiser, P Knöbl, C Fonatsch, O A Haas, G Mitterbauer, A Weltermann, K Geissler, P Valent, W Sperr, I Pabinger, K Lechner & U Jaeger
Abstract  |  Full text  |  PDF 2059
Late autologous transplantation in chronic myelogenous leukemia with peripheral blood progenitor cells mobilized by G-CSF and interferon-alpha FREE
M Michallet, A Thiébaut, I Philip, C Charrin, C Vigouroux, X Thomas, K Bilger, A Belhabri, D Guyotat, B Corront, B Salles, C Dumontet, P Y Péaud, J P Vilque, A Devidas & D Fière
Abstract  |  Full text  |  PDF 2064
Protean clinical manifestations in children with leukemias containing MLL-AF10 fusion FREE
L Gore, J Ess, M A Bitter, L McGavran, L Meltesen, Q Wei & S P Hunger
Abstract  |  Full text  |  PDF 2070
Disease- and treatment-related elevation of the neurodegenerative marker tau in children with hematological malignancies FREE
S W Van Gool, E Van Kerschaver, P Brock, H Pottel, F Hulstaert, E Vanmechelen, A Uyttebroeck, A Van De Voorde & H Vanderstichele
Abstract  |  Full text  |  PDF 2076
Phase I study of cinchonine, a multidrug resistance reversing agent, combined with the CHVP regimen in relapsed and refractory lymphoproliferative syndromes FREE
E Solary, L Mannone, D Moreau, D Caillot, R-O Casasnovas, H Guy, M Grandjean, J-E Wolf, F André, P Fenaux, P Canal, B Chauffert, A Wotawa, M Bayssas & P Genne
Abstract  |  Full text  |  PDF 2085
Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells FREE
F E Bertrand, C E Eckfeldt, A S Lysholm & T W LeBien
Abstract  |  Full text  |  PDF 2095
Fine characterization of childhood and adult acute lymphoblastic leukemia (ALL) by a proB and preB surrogate light chain-specific mAb and a proposal for a new B cell ALL classification FREE
B Lemmers, C Arnoulet, C Fossat, H Chambost, D Sainty, J Gabert & C Schiff
Abstract  |  Full text  |  PDF 2103
A transient dephosphorylation of JAK1 and JAK2 characterises the early-phase response of murine erythroleukemia cells to the differentiation inducer hexamethylenebisacetamide FREE
A Arcangeli, L Fontana, O Crociani, A Cherubini, G Hofmann, E Piccini, S Polvani, M D'Amico, M Carlà & M Olivotto
Abstract  |  Full text  |  PDF 2112
Modifications in phospholipase D activity and isoform expression occur upon maturation and differentiation in vivo and in vitro in human myeloid cells FREE
M El Marjou, V Montalescot, A Buzyn & B Geny
Abstract  |  Full text  |  PDF 2118
Human mortalin (HSPA9): a candidate for the myeloid leukemia tumor suppressor gene on 5q31 FREE
H Xie, Z Hu, B Chyna, S K Horrigan & C A Westbrook
Abstract  |  Full text  |  PDF 2128
Proliferative status of primitive hematopoietic progenitors from patients with acute myelogenous leukemia (AML) FREE
Y Guan & D E Hogge
Abstract  |  Full text  |  PDF 2135
Genetic instability is associated with histological transformation of follicle center lymphoma FREE
M Nagy, M Balázs, Z Ádám, Z Petkó, B Tímár, Z Szereday, T László, R A Warnke & A Matolcsy
Abstract  |  Full text  |  PDF 2142
Resistance to CD95-mediated apoptosis through constitutive c-FLIP expression in a non-Hodgkin's lymphoma B cell line FREE
M Irisarri, J Plumas, T Bonnefoix, M-C Jacob, C Roucard, M-A Pasquier, J-J Sotto & A Lajmanovich
Abstract  |  Full text  |  PDF 2149
A prospective study of intensive induction therapy with high-dose consolidation in patients with aggressive non-Hodgkin's lymphoma and two or three adverse prognostic factors FREE
C Dumontet, C Thieblemont, D Espinouse, F Bouafia, O Hequet, G Salles & B Coiffier
Abstract  |  Full text  |  PDF 2159
Bio-Technical Methods Section (BTS)
mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method FREE
M G Rots, J C Willey, G Jansen, C H Van Zantwijk, P Noordhuis, J P DeMuth, E Kuiper, A J P Veerman, R Pieters & G J Peters
Abstract  |  Full text  |  PDF 2166
Detection of hTERT protein by flow cytometry FREE
A S M Ali, R Chopra, J Robertson & N G Testa
Abstract  |  Full text  |  PDF 2176
Extensive characterization of dendritic cells generated in serum-free conditions: regulation of soluble antigen uptake, apoptotic tumor cell phagocytosis, chemotaxis and T cell activation during maturation in vitro FREE
K Tarte, G Fiol, J-F Rossi & B Klein
Abstract  |  Full text  |  PDF 2182
Spotlight on Long-Term Results of Pediatric ALL Clinical Trials from 12 Study Groups World Wide
Long-term results of large prospective trials in childhood acute lymphoblastic leukemia FREE
M Schrappe, B Camitta & C-H Pui
Abstract  |  Full text  |  PDF 2193
Spotlight on Long-Term Results of Pediatric ALL Clinical Trials from 12 Study Groups World Wide
Note from the Editor FREE
N Muller-Bérat MD
Abstract  |  Full text  |  PDF 2195
Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) Acute Lymphoblastic Leukemia Studies, 1982-1995 FREE
V Conter, M Aricò, M G Valsecchi, G Basso, A Biondi, E Madon, F Mandelli, G Paolucci, A Pession, C Rizzari, R Rondelli, L Zanesco & G Masera for the Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP)
Abstract  |  Full text  |  PDF 2196
Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995 FREE
M Schrappe, A Reiter, M Zimmermann, J Harbott, W-D Ludwig, G Henze, H Gadner, E Odenwald & H Riehm
Abstract  |  Full text  |  PDF 2205
Children's Cancer Group trials in childhood acute lymphoblastic leukemia: 1983-1995 FREE
P S Gaynon, M E Trigg, N A Heerema, M G Sensel, H N Sather, G D Hammond & W A Bleyer
Abstract  |  Full text  |  PDF 2223
Co-operative study group for childhood acute lymphoblastic leukemia (COALL): long-term follow-up of trials 82, 85, 89 and 92 FREE
D O Harms & G E Janka-Schaub on behalf of the COALL Study Group
Abstract  |  Full text  |  PDF 2234
Long-term follow-up of Dutch Childhood Leukemia Study Group (DCLSG) protocols for children with acute lymphoblastic leukemia, 1984-1991 FREE
W A Kamps, A J P Veerman, E R van Wering, J F van Weerden, R Slater & A van der Does-van den Berg
Abstract  |  Full text  |  PDF 2240
Results of Dana-Farber Cancer Institute Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1981-1995) FREE
L B Silverman, L Declerck, R D Gelber, V Kimball Dalton, B L Asselin, R D Barr, L A Clavell, C A Hurwitz, A Moghrabi, Y Samson, M A Schorin, J M Lipton, H J Cohen & S E Sallan
Abstract  |  Full text  |  PDF 2247
Long-term results of three randomized trials (58831, 58832, 58881) in childhood acute lymphoblastic leukemia: a CLCG-EORTC report FREE
E Vilmer, S Suciu, A Ferster, Y Bertrand, H Cavé, A Thyss, Y Benoit, N Dastugue, M Fournier, G Souillet, A-M Manel, A Robert, B Nelken, F Millot, P Lutz, X Rialland, F Mechinaud, P Boutard, C Behar, J-M Chantraine, E Plouvier, G Laureys, P Brock, A Uyttebroeck, G Margueritte, D Plantaz, L Norton, N Francotte, J Gyselinck, C Waterkeyn, G Solbu, N Philippe & J Otten
Abstract  |  Full text  |  PDF 2257
Improving outcome through two decades in childhood ALL in the Nordic countries: the impact of high-dose methotrexate in the reduction of CNS irradiation FREE
G Gustafsson, K Schmiegelow, E Forestier, N Clausen, A Glomstein, G Jonmundsson, L Mellander, A Mäkipernaa, R Nygaard & U M Saarinen-Pihkala on behalf of the Nordic Society of Pediatric Haematology & Oncology (NOPHO)
Abstract  |  Full text  |  PDF 2267
Long-term results of treatment studies for childhood acute lymphoblastic leukemia: Pediatric Oncology Group studies from 1986-1994 FREE
K W Maloney, J J Shuster, S Murphy, J Pullen & B A Camitta
Abstract  |  Full text  |  PDF 2276
Long-term results of Total Therapy studies 11, 12 and 13A for childhood acute lymphoblastic leukemia at St Jude Children's Research Hospital FREE
C-H Pui, J M Boyett, G K Rivera, M L Hancock, J T Sandlund, R C Ribeiro, J E Rubnitz, F G Behm, S C Raimondi, A Gajjar, B Razzouk, D Campana, L E Kun, M V Relling & W E Evans
Abstract  |  Full text  |  PDF 2286
Long-term follow-up of childhood acute lymphoblastic leukemia in Tokyo Children's Cancer Study Group 1981-1995 FREE
M Tsuchida, K Ikuta, R Hanada, T Saito, K Isoyama, K Sugita, Y Toyoda, A Manabe, K Koike, A Kinoshita, M Maeda, K Ishimoto, T Sato, Y Okimoto, T Kaneko, M Kajiwara, M Sotomatsu, Y Hayashi, H Yabe, R Hosoya, Y Hoshi, M Ohira, F Bessho, Y Tsunematsu, I Tsukimoto & S Nakazawa for the Tokyo Children's Cancer Study Group
Abstract  |  Full text  |  PDF 2295
Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute lymphoblastic leukaemia, 1980-1997 FREE
O B Eden, G Harrison, S Richards, J S Lilleyman, C C Bailey, J M Chessells, I M Hann, F G H Hill & B E S Gibson on behalf of the Medical Research Council Childhood Leukaemia Working Party
Abstract  |  Full text  |  PDF 2307
Correspondence
An unusual presentation of a case of T cell angiotropic (intravascular) lymphoma FREE
G Isimbaldi, L Corral, S Songia, M G Valente, S De Bianchi & A Biondi
Abstract  |  Full text  |  PDF 2321
Intrathecal mitozantrone has to be prohibited FREE
J H Dalle, A Lambilliotte, A S Defachelles, F Mazingue & B Nelken
Abstract  |  Full text  |  PDF 2323
Is there any genetic susceptibility to acute promyelocytic leukemia? FREE
X Thomas
Abstract  |  Full text  |  PDF 2324
Author Index
Author Index FREE
Abstract  |  PDF 2327
Keyword index FREE
Abstract  |  PDF 2337
December 2000, Volume 14, Number 12
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