Original Article

The Journal of Antibiotics (2008) 61, 563–567; doi:10.1038/ja.2008.75

Sterelactones: New Isolactarane Type Sesquiterpenoids with Antifungal Activity from Stereum sp. IBWF 01060

Till Opatz1, Heinz Kolshorn2 and Heidrun Anke3

  1. 1Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany
  2. 2Institute of Organic Chemistry, University of Mainz, Duesbergweg 10-14, 55128 Mainz, Germany
  3. 3Institute of Biotechnology and Drug Research, Erwin-Schrödinger-Str. 56, 67663 Kaiserslautern, Germany

Correspondence: Till Opatz, Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany. E-mail: opatz@chemie.unihamburg.de

Received 24 June 2008; Accepted 29 August 2008.



Four members of a new family of tetracyclic sesquiterenoids possessing the isolactarane skeleton have been isolated from mycelial cultures of Stereum sp. IBWF 01060. Their structure elucidation and their antifungal activity against several plant pathogens as well as other microorganisms are reported.


sesquiterpenoids, isolactaranes, fungicide, structure elucidation, NMR spectroscopy



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