Gene Therapy

Enabling Technologies

Overexpression of Ad5 precursor terminal protein accelerates recombinant adenovirus packaging and amplification in HEK-293 packaging cells

N Wu
H Zhang
T-C He
Enabling Technologies01 May 2014
TALEN-mediated editing of endogenous T-cell receptors facilitates efficient reprogramming of T lymphocytes by lentiviral gene transfer

B Berdien
U Mock
B Fehse
Enabling Technologies27 Mar 2014
An integration-defective lentivirus-based resource for site-specific targeting of an edited safe-harbour locus in the human genome

R Torres
A Garcia
J C Ramirez
Enabling Technologies06 Feb 2014
Injection parameters and virus dependent choice of promoters to improve neuron targeting in the nonhuman primate brain

W Lerchner
B Corgiat
B J Richmond
Enabling Technologies09 Jan 2014
Quantitative morphological comparison of axon-targeting strategies for gene therapies directed to the nigro-striatal projection

S Padmanabhan
T Kareva
R E Burke
Enabling Technologies05 Dec 2013
Minimal piggyBac vectors for chromatin integration

V Solodushko
V Bitko
B Fouty
Enabling Technologies17 Oct 2013
Quantification of HSV-1-mediated expression of the ferritin MRI reporter in the mouse brain

B Iordanova
W F Goins
E T Ahrens
Enabling Technologies20 Sept 2012
Bioprocess development for canine adenovirus type 2 vectors

P Fernandes
C Peixoto
P M Alves
Enabling Technologies05 Jul 2012
Ultrasound-targeted microbubble destruction enhances naked plasmid DNA transfection in rabbit Achilles tendons in vivo

L Qiu
L Zhang
L Lin
Enabling Technologies27 Oct 2011
Mitochondrial gene replacement in human pluripotent stem cell-derived neural progenitors

S Iyer
E Xiao
R R Rao
Enabling Technologies15 Sept 2011
Delivery of functional DNA and messenger RNA to mammalian phagocytic cells by recombinant yeast

B Walch
T Breinig
F Breinig
Enabling Technologies25 Aug 2011
Scale-up and manufacturing of clinical-grade self-inactivating γ-retroviral vectors by transient transfection

J C M van der Loo
W P Swaney
P Malik
Enabling Technologies14 Jul 2011
Efficient cochlear gene transfection in guinea-pigs with adeno-associated viral vectors by partial digestion of round window membrane

H Wang
R Murphy
J Wang
Enabling Technologies23 Jun 2011
Synchrotron phase-contrast X-ray imaging reveals fluid dosing dynamics for gene transfer into mouse airways

M Donnelley
K K W Siu
D W Parsons
Enabling Technologies09 Jun 2011
RETRACTED ARTICLE: Targeted suicide gene therapy for glioma using human embryonic stem cell-derived neural stem cells genetically modified by baculoviral vectors

Y Zhao
D H Lam
S Wang
Enabling Technologies02 Jun 2011
CTF/NF1 transcription factors act as potent genetic insulators for integrating gene transfer vectors

A Gaussin
U Modlich
N Mermod
Enabling Technologies12 May 2011
Self-inactivating helper virus for the production of high-capacity adenoviral vectors

M Gonzalez-Aparicio
I Mauleon
R Hernandez-Alcoceba
Enabling Technologies28 Apr 2011
CDK4 and cyclin D1 allow human myogenic cells to recapture growth property without compromising differentiation potential

K Shiomi
T Kiyono
N Hashimoto
Enabling Technologies14 Apr 2011
The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor

Z Jin
S Maiti
L J N Cooper
Enabling Technologies31 Mar 2011
Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection

Y Zhang
Z Qu
I D Horak
Enabling TechnologiesOpen Access23 Dec 2010

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